diff --git a/Ladybird/CMakeLists.txt b/Ladybird/CMakeLists.txt
index 23def84cfc2..2a52717bf08 100644
--- a/Ladybird/CMakeLists.txt
+++ b/Ladybird/CMakeLists.txt
@@ -188,7 +188,7 @@ function(set_helper_process_properties)
         # Store helper processes in the same bundle directory as the main application
         set_target_properties(${targets} PROPERTIES RUNTIME_OUTPUT_DIRECTORY "$<TARGET_FILE_DIR:ladybird>")
     else()
-        set_target_properties(${targets} PROPERTIES RUNTIME_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${CMAKE_INSTALL_LIBEXECDIR}")
+        set_target_properties(${targets} PROPERTIES RUNTIME_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${IN_BUILD_PREFIX}${CMAKE_INSTALL_LIBEXECDIR}")
 
         if (NOT CMAKE_INSTALL_LIBEXECDIR STREQUAL "libexec")
             set_source_files_properties(Utilities.cpp PROPERTIES COMPILE_DEFINITIONS LADYBIRD_LIBEXECDIR="${CMAKE_INSTALL_LIBEXECDIR}")
@@ -257,7 +257,7 @@ create_ladybird_bundle(ladybird)
 set_helper_process_properties(${ladybird_helper_processes})
 
 include(cmake/ResourceFiles.cmake)
-set(resource_base_dir "${CMAKE_BINARY_DIR}/${CMAKE_INSTALL_DATADIR}/Lagom")
+set(resource_base_dir "${CMAKE_BINARY_DIR}/${IN_BUILD_PREFIX}${CMAKE_INSTALL_DATADIR}/Lagom")
 if (APPLE)
     set(resource_base_dir "$<TARGET_BUNDLE_DIR:ladybird>/Contents/Resources")
 endif()
diff --git a/Meta/CMake/lagom_install_options.cmake b/Meta/CMake/lagom_install_options.cmake
index b9e3baaa666..0c29e14ec8e 100644
--- a/Meta/CMake/lagom_install_options.cmake
+++ b/Meta/CMake/lagom_install_options.cmake
@@ -8,11 +8,18 @@ endif()
 
 include(GNUInstallDirs) # make sure to include before we mess w/RPATH
 
+# Handle multi-config generators (e.g. MSVC, Xcode, Ninja Multi-Config)
+get_property(is_multi_config GLOBAL PROPERTY GENERATOR_IS_MULTI_CONFIG)
+set(IN_BUILD_PREFIX "")
+if (is_multi_config)
+    set(IN_BUILD_PREFIX "$<CONFIG>/")
+endif()
+
 # Mirror the structure of the installed tree to ensure that rpaths
 # always remain valid.
-set(CMAKE_RUNTIME_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${CMAKE_INSTALL_BINDIR}")
-set(CMAKE_LIBRARY_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${CMAKE_INSTALL_LIBDIR}")
-set(CMAKE_ARCHIVE_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${CMAKE_INSTALL_LIBDIR}")
+set(CMAKE_RUNTIME_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${IN_BUILD_PREFIX}${CMAKE_INSTALL_BINDIR}")
+set(CMAKE_LIBRARY_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${IN_BUILD_PREFIX}${CMAKE_INSTALL_LIBDIR}")
+set(CMAKE_ARCHIVE_OUTPUT_DIRECTORY "${CMAKE_BINARY_DIR}/${IN_BUILD_PREFIX}${CMAKE_INSTALL_LIBDIR}")
 
 set(CMAKE_SKIP_BUILD_RPATH FALSE)
 set(CMAKE_BUILD_WITH_INSTALL_RPATH TRUE)