diff --git a/ghost/admin/app/components/modals/edit-newsletter.js b/ghost/admin/app/components/modals/edit-newsletter.js
index 0a058ad24e..324143f387 100644
--- a/ghost/admin/app/components/modals/edit-newsletter.js
+++ b/ghost/admin/app/components/modals/edit-newsletter.js
@@ -1,9 +1,13 @@
 import Component from '@glimmer/component';
+import ConfirmNewsletterEmailModal from './edit-newsletter/confirm-newsletter-email';
 import {action} from '@ember/object';
+import {inject as service} from '@ember/service';
 import {task} from 'ember-concurrency';
 import {tracked} from '@glimmer/tracking';
 
 export default class EditNewsletterModal extends Component {
+    @service modals;
+
     static modalOptions = {
         className: 'fullscreen-modal-full-overlay fullscreen-modal-portal-settings'
     };
@@ -31,8 +35,17 @@ export default class EditNewsletterModal extends Component {
     @task
     *saveTask() {
         try {
+            const newEmail = this.args.data.newsletter.senderEmail;
+
             const result = yield this.args.data.newsletter.save();
 
+            if (result._meta?.sent_email_verification) {
+                yield this.modals.open(ConfirmNewsletterEmailModal, {
+                    newEmail,
+                    currentEmail: this.args.data.newsletter.senderEmail
+                });
+            }
+
             this.args.data.afterSave?.(result);
 
             return result;
diff --git a/ghost/admin/app/components/modals/edit-newsletter/confirm-newsletter-email.hbs b/ghost/admin/app/components/modals/edit-newsletter/confirm-newsletter-email.hbs
new file mode 100644
index 0000000000..6ec8e7010a
--- /dev/null
+++ b/ghost/admin/app/components/modals/edit-newsletter/confirm-newsletter-email.hbs
@@ -0,0 +1,26 @@
+<div class="modal-content">
+    <header class="modal-header" data-test-modal="confirm-newsletter-email">
+        <h1>Confirm newsletter email address</h1>
+    </header>
+    <button type="button" class="close" role="button" title="Close" {{on "click" @close}}>{{svg-jar "close"}}<span class="hidden">Close</span></button>
+
+    <div class="modal-body">
+        <p>
+            We've sent a confirmation email to <strong>{{@data.newEmail}}</strong>.
+            Until the address has been verified newsletters will be sent from the
+            {{if @data.currentEmail "previous" "default"}} email address
+            ({{full-email-address (or @data.currentEmail "noreply")}}).
+        </p>
+    </div>
+
+    <div class="modal-footer">
+        <button
+            type="button"
+            class="gh-btn"
+            {{on "click" @close}}
+            {{on-key "Enter"}}
+        >
+            <span>Ok</span>
+        </button>
+    </div>
+</div>
\ No newline at end of file
diff --git a/ghost/admin/app/components/modals/edit-newsletter/verify-newsletter-email.hbs b/ghost/admin/app/components/modals/edit-newsletter/verify-newsletter-email.hbs
new file mode 100644
index 0000000000..9bf758b998
--- /dev/null
+++ b/ghost/admin/app/components/modals/edit-newsletter/verify-newsletter-email.hbs
@@ -0,0 +1,34 @@
+<div class="modal-content">
+    <header class="modal-header" data-test-modal="verify-newsletter-email">
+        <h1>Verifying newsletter email address</h1>
+    </header>
+    <button type="button" class="close" role="button" title="Close" {{on "click" @close}}>{{svg-jar "close"}}<span class="hidden">Close</span></button>
+
+    <div class="modal-body">
+        {{#if this.verifyEmailTask.isRunning}}
+            <div class="flex justify-center flex-auto">
+                <div class="gh-loading-spinner"></div>
+            </div>
+        {{else if this.newsletter}}
+            <p>
+                Success! From address for newsletter
+                "<LinkTo @route="settings.members-email-labs.edit-newsletter" @model={{this.newsletter.id}}>{{this.newsletter.name}}</LinkTo>"
+                changed to <strong>{{this.newsletter.senderEmail}}</strong>
+            </p>
+        {{else if this.error}}
+            <p>Verification failed:</p>
+            <p>{{this.error}}</p>
+        {{/if}}
+    </div>
+
+    <div class="modal-footer">
+        <button
+            type="button"
+            class="gh-btn"
+            {{on "click" @close}}
+            {{on-key "Enter"}}
+        >
+            <span>Ok</span>
+        </button>
+    </div>
+</div>
\ No newline at end of file
diff --git a/ghost/admin/app/components/modals/edit-newsletter/verify-newsletter-email.js b/ghost/admin/app/components/modals/edit-newsletter/verify-newsletter-email.js
new file mode 100644
index 0000000000..b06c627028
--- /dev/null
+++ b/ghost/admin/app/components/modals/edit-newsletter/verify-newsletter-email.js
@@ -0,0 +1,49 @@
+import Component from '@glimmer/component';
+import {action} from '@ember/object';
+import {inject as service} from '@ember/service';
+import {task} from 'ember-concurrency';
+import {tracked} from '@glimmer/tracking';
+
+export default class VerifyNewsletterEmail extends Component {
+    @service ajax;
+    @service ghostPaths;
+    @service router;
+    @service store;
+
+    @tracked error = null;
+    @tracked newsletter = null;
+
+    constructor() {
+        super(...arguments);
+        this.verifyEmailTask.perform(this.args.data.token);
+
+        this.router.on('routeDidChange', this.handleRouteChange);
+    }
+
+    willDestroy() {
+        super.willDestroy(...arguments);
+        this.router.off('routeDidChange', this.handleRouteChange);
+    }
+
+    @task
+    *verifyEmailTask(token) {
+        try {
+            const url = this.ghostPaths.url.api('newsletters', 'verify-email');
+
+            const response = yield this.ajax.put(url, {data: {token}});
+
+            if (response.newsletters) {
+                this.store.pushPayload('newsletter', response);
+                const newsletter = this.store.peekRecord('newsletter', response.newsletters[0].id);
+                this.newsletter = newsletter;
+            }
+        } catch (e) {
+            this.error = e.message;
+        }
+    }
+
+    @action
+    handleRouteChange() {
+        this.args.close();
+    }
+}
diff --git a/ghost/admin/app/components/settings/members-email-labs.js b/ghost/admin/app/components/settings/members-email-labs.js
index eb273a3f93..4c9dfb5b4c 100644
--- a/ghost/admin/app/components/settings/members-email-labs.js
+++ b/ghost/admin/app/components/settings/members-email-labs.js
@@ -1,7 +1,6 @@
 import Component from '@glimmer/component';
 import {action} from '@ember/object';
 import {inject as service} from '@ember/service';
-import {task} from 'ember-concurrency';
 import {tracked} from '@glimmer/tracking';
 
 const US = {flag: '🇺🇸', name: 'US', baseUrl: 'https://api.mailgun.net/v3'};
@@ -9,8 +8,6 @@ const EU = {flag: '🇪🇺', name: 'EU', baseUrl: 'https://api.eu.mailgun.net/v
 
 export default class MembersEmailLabs extends Component {
     @service config;
-    @service ghostPaths;
-    @service ajax;
     @service settings;
 
     // set recipientsSelectValue as a static property because within this
@@ -19,41 +16,12 @@ export default class MembersEmailLabs extends Component {
     // from settings as it would equate to "none"
     @tracked recipientsSelectValue = this._getDerivedRecipientsSelectValue();
 
-    @tracked showFromAddressConfirmation = false;
-
     mailgunRegions = [US, EU];
 
-    replyAddresses = [
-        {
-            label: 'Newsletter email address (' + this.fromAddress + ')',
-            value: 'newsletter'
-        },
-        {
-            label: 'Support email address (' + this.supportAddress + ')',
-            value: 'support'
-        }
-    ];
-
     get emailNewsletterEnabled() {
         return this.settings.get('editorDefaultEmailRecipients') !== 'disabled';
     }
 
-    get emailPreviewVisible() {
-        return this.recipientsSelectValue !== 'none';
-    }
-
-    get selectedReplyAddress() {
-        return this.replyAddresses.findBy('value', this.settings.get('membersReplyAddress'));
-    }
-
-    get disableUpdateFromAddressButton() {
-        const savedFromAddress = this.settings.get('membersFromAddress') || '';
-        if (!savedFromAddress.includes('@') && this.config.emailDomain) {
-            return !this.fromAddress || (this.fromAddress === `${savedFromAddress}@${this.config.emailDomain}`);
-        }
-        return !this.fromAddress || (this.fromAddress === savedFromAddress);
-    }
-
     get mailgunRegion() {
         if (!this.settings.get('mailgunBaseUrl')) {
             return US;
@@ -72,11 +40,6 @@ export default class MembersEmailLabs extends Component {
         };
     }
 
-    @action
-    toggleFromAddressConfirmation() {
-        this.showFromAddressConfirmation = !this.showFromAddressConfirmation;
-    }
-
     @action
     setMailgunDomain(event) {
         this.settings.set('mailgunDomain', event.target.value);
@@ -98,11 +61,6 @@ export default class MembersEmailLabs extends Component {
         this.settings.set('mailgunBaseUrl', region.baseUrl);
     }
 
-    @action
-    setFromAddress(fromAddress) {
-        this.setEmailAddress('fromAddress', fromAddress);
-    }
-
     @action
     toggleEmailTrackOpens(event) {
         if (event) {
@@ -129,13 +87,6 @@ export default class MembersEmailLabs extends Component {
         this.recipientsSelectValue = this._getDerivedRecipientsSelectValue();
     }
 
-    @action
-    setReplyAddress(event) {
-        const newReplyAddress = event.value;
-
-        this.settings.set('membersReplyAddress', newReplyAddress);
-    }
-
     @action
     setDefaultEmailRecipients(value) {
         // Update the underlying setting properties to match the selected recipients option
@@ -169,24 +120,6 @@ export default class MembersEmailLabs extends Component {
         this.settings.set('editorDefaultEmailRecipientsFilter', filter);
     }
 
-    @task({drop: true})
-    *updateFromAddress() {
-        let url = this.ghostPaths.url.api('/settings/members/email');
-        try {
-            const response = yield this.ajax.post(url, {
-                data: {
-                    email: this.fromAddress,
-                    type: 'fromAddressUpdate'
-                }
-            });
-            this.toggleFromAddressConfirmation();
-            return response;
-        } catch (e) {
-            // Failed to send email, retry
-            return false;
-        }
-    }
-
     _getDerivedRecipientsSelectValue() {
         const defaultEmailRecipients = this.settings.get('editorDefaultEmailRecipients');
         const defaultEmailRecipientsFilter = this.settings.get('editorDefaultEmailRecipientsFilter');
diff --git a/ghost/admin/app/controllers/settings/members-email-labs.js b/ghost/admin/app/controllers/settings/members-email-labs.js
index c73308202f..4eac4cbac1 100644
--- a/ghost/admin/app/controllers/settings/members-email-labs.js
+++ b/ghost/admin/app/controllers/settings/members-email-labs.js
@@ -1,37 +1,14 @@
 import Controller from '@ember/controller';
-import {action} from '@ember/object';
 import {inject as service} from '@ember/service';
 import {task} from 'ember-concurrency';
 import {tracked} from '@glimmer/tracking';
 
 export default class MembersEmailLabsController extends Controller {
-    @service config;
-    @service session;
     @service settings;
 
-    // from/supportAddress are set here so that they can be reset to saved values on save
-    // to avoid it looking like they've been saved when they have a separate update process
-    @tracked fromAddress = '';
-    @tracked supportAddress = '';
+    queryParams = ['verifyEmail'];
 
-    @action
-    setEmailAddress(property, email) {
-        this[property] = email;
-    }
-
-    parseEmailAddress(address) {
-        const emailAddress = address || 'noreply';
-        // Adds default domain as site domain
-        if (emailAddress.indexOf('@') < 0 && this.config.emailDomain) {
-            return `${emailAddress}@${this.config.emailDomain}`;
-        }
-        return emailAddress;
-    }
-
-    resetEmailAddresses() {
-        this.fromAddress = this.parseEmailAddress(this.settings.get('membersFromAddress'));
-        this.supportAddress = this.parseEmailAddress(this.settings.get('membersSupportAddress'));
-    }
+    @tracked verifyEmail = null;
 
     @task({drop: true})
     *saveSettings() {
diff --git a/ghost/admin/app/models/newsletter.js b/ghost/admin/app/models/newsletter.js
index 1557bdcc77..9a69254add 100644
--- a/ghost/admin/app/models/newsletter.js
+++ b/ghost/admin/app/models/newsletter.js
@@ -27,4 +27,8 @@ export default class Newsletter extends Model.extend(ValidationEngine) {
     @attr({defaultValue: 'sans_serif'}) bodyFontCategory;
     @attr() footerContent;
     @attr({defaultValue: true}) showBadge;
+
+    // HACK - not a real model attribute but a workaround for Ember Data not
+    //        exposing meta from save responses
+    @attr _meta;
 }
diff --git a/ghost/admin/app/routes/settings/members-email-labs.js b/ghost/admin/app/routes/settings/members-email-labs.js
index 32c9c5a225..9ef9d9c3d0 100644
--- a/ghost/admin/app/routes/settings/members-email-labs.js
+++ b/ghost/admin/app/routes/settings/members-email-labs.js
@@ -1,5 +1,6 @@
 import AdminRoute from 'ghost-admin/routes/admin';
 import ConfirmUnsavedChangesModal from '../../components/modals/confirm-unsaved-changes';
+import VerifyNewsletterEmail from '../../components/modals/edit-newsletter/verify-newsletter-email';
 import {action} from '@ember/object';
 import {inject as service} from '@ember/service';
 
@@ -9,30 +10,37 @@ export default class MembersEmailLabsRoute extends AdminRoute {
     @service notifications;
     @service settings;
 
+    queryParams = {
+        verifyEmail: {
+            replace: true
+        }
+    };
+
     confirmModal = null;
     hasConfirmed = false;
 
-    beforeModel(transition) {
+    beforeModel() {
         super.beforeModel(...arguments);
 
         if (!this.feature.multipleNewsletters) {
             return this.transitionTo('settings.members-email');
         }
-
-        if (transition.to.queryParams?.fromAddressUpdate === 'success') {
-            this.notifications.showAlert(
-                `Newsletter email address has been updated`,
-                {type: 'success', key: 'members.settings.from-address.updated'}
-            );
-        }
     }
 
     model() {
         return this.settings.reload();
     }
 
-    setupController(controller) {
-        controller.resetEmailAddresses();
+    afterModel(model, transition) {
+        if (transition.to.queryParams.verifyEmail) {
+            this.modals.open(VerifyNewsletterEmail, {
+                token: transition.to.queryParams.verifyEmail
+            });
+
+            // clear query param so it doesn't linger and cause problems re-entering route
+            transition.abort();
+            return this.transitionTo('settings.members-email-labs', {queryParams: {verifyEmail: null}});
+        }
     }
 
     @action
diff --git a/ghost/admin/app/serializers/newsletter.js b/ghost/admin/app/serializers/newsletter.js
new file mode 100644
index 0000000000..d09f69783f
--- /dev/null
+++ b/ghost/admin/app/serializers/newsletter.js
@@ -0,0 +1,27 @@
+/* eslint-disable camelcase */
+import ApplicationSerializer from './application';
+
+export default class MemberSerializer extends ApplicationSerializer {
+    // HACK: Ember Data doesn't expose `meta` properties consistently
+    //  - https://github.com/emberjs/data/issues/2905
+    //
+    // We need the `meta` data returned when saving so we extract it and dump
+    // it onto the model as an attribute then delete it again when serializing.
+    normalizeResponse() {
+        const json = super.normalizeResponse(...arguments);
+
+        if (json.meta && json.data.attributes) {
+            json.data.attributes._meta = json.meta;
+        }
+
+        return json;
+    }
+
+    serialize() {
+        const json = super.serialize(...arguments);
+
+        delete json._meta;
+
+        return json;
+    }
+}
diff --git a/ghost/admin/app/templates/settings/members-email-labs.hbs b/ghost/admin/app/templates/settings/members-email-labs.hbs
index 1bcc332c3b..4c2511febf 100644
--- a/ghost/admin/app/templates/settings/members-email-labs.hbs
+++ b/ghost/admin/app/templates/settings/members-email-labs.hbs
@@ -20,11 +20,7 @@
 
     <section class="view-container settings-debug">
         <div class="gh-setting-liquid-section">
-            <Settings::MembersEmailLabs
-                @fromAddress={{this.fromAddress}}
-                @supportAddress={{this.supportAddress}}
-                @setEmailAddress={{this.setEmailAddress}}
-            />
+            <Settings::MembersEmailLabs />
         </div>
     </section>
 </section>
\ No newline at end of file
diff --git a/ghost/admin/mirage/config/newsletters.js b/ghost/admin/mirage/config/newsletters.js
index 1ef90ccd40..add2231310 100644
--- a/ghost/admin/mirage/config/newsletters.js
+++ b/ghost/admin/mirage/config/newsletters.js
@@ -1,8 +1,77 @@
+import {camelize} from '@ember/string';
 import {paginatedResponse} from '../utils';
 
 export default function mockNewsletters(server) {
-    server.post('/newsletters/');
     server.get('/newsletters/', paginatedResponse('newsletters'));
     server.get('/newsletters/:id/');
-    server.put('/newsletters/:id/');
+
+    server.post('/newsletters/', function ({newsletters}) {
+        const attrs = this.normalizedRequestAttrs();
+
+        // sender email can't be set without verification
+        const senderEmail = attrs.senderEmail;
+        attrs.senderEmail = null;
+
+        const newsletter = newsletters.create(attrs);
+
+        // workaround for mirage output of meta
+        const collection = newsletters.where({id: newsletter.id});
+
+        if (senderEmail) {
+            collection.meta = {
+                sent_email_verification: ['sender_email']
+            };
+        }
+
+        return collection;
+    });
+
+    server.put('/newsletters/:id/', function ({newsletters}, {params}) {
+        const attrs = this.normalizedRequestAttrs();
+        const newsletter = newsletters.find(params.id);
+
+        const previousSenderEmail = newsletter.senderEmail;
+        const newSenderEmail = attrs.senderEmail;
+
+        // sender email can't be changed without verification
+        if (newSenderEmail && newSenderEmail !== previousSenderEmail) {
+            attrs.senderEmail = previousSenderEmail;
+        }
+
+        newsletter.update(attrs);
+
+        // workaround for mirage output of meta
+        const collection = newsletters.where({id: newsletter.id});
+
+        if (newSenderEmail && newSenderEmail !== previousSenderEmail) {
+            collection.meta = {
+                sent_email_verification: ['sender_email']
+            };
+
+            const tokenData = {
+                id: newsletter.id,
+                email: newSenderEmail,
+                type: 'sender_email'
+            };
+            const token = btoa(JSON.stringify(tokenData));
+            const baseUrl = window.location.href.replace(window.location.hash, '');
+            const verifyUrl = `${baseUrl}settings/members-email-labs/?verifyEmail=${token}`;
+            // eslint-disable-next-line
+            console.warn('Verification email sent. Mocked verification URL:', verifyUrl);
+        }
+
+        return collection;
+    });
+
+    // verify email update
+    server.put('/newsletters/verify-email/', function ({newsletters}, request) {
+        const requestBody = JSON.parse(request.requestBody);
+        const tokenData = JSON.parse(atob(requestBody.token));
+
+        const newsletter = newsletters.find(tokenData.id);
+
+        newsletter[camelize(tokenData.type)] = tokenData.email;
+
+        return newsletter.save();
+    });
 }
diff --git a/ghost/admin/mirage/scenarios/default.js b/ghost/admin/mirage/scenarios/default.js
index 8ebf793537..c2a38f0a80 100644
--- a/ghost/admin/mirage/scenarios/default.js
+++ b/ghost/admin/mirage/scenarios/default.js
@@ -9,4 +9,30 @@ export default function (server) {
     server.create('integration', {name: 'Demo'});
 
     server.createList('member', 125);
+
+    // sites always have a default newsletter
+    server.create('newsletter', {
+        name: 'Site title',
+        slug: 'site-title',
+        description: 'Default newsletter created during setup',
+
+        senderName: 'Site title',
+        senderEmail: null,
+        senderReplyTo: 'newsletter',
+
+        status: 'active',
+        recipientFilter: null,
+        subscribeOnSignup: true,
+        sortOrder: 0,
+
+        headerImage: null,
+        showHeaderIcon: true,
+        showHeaderTitle: true,
+        titleFontCategory: 'sans_serif',
+        titleAlignment: 'center',
+        showFeatureImage: true,
+        bodyFontCategory: 'sans_serif',
+        footerContent: null,
+        showBadge: true
+    });
 }
diff --git a/ghost/admin/mirage/serializers/application.js b/ghost/admin/mirage/serializers/application.js
index 6874381bcd..1cc58e128a 100644
--- a/ghost/admin/mirage/serializers/application.js
+++ b/ghost/admin/mirage/serializers/application.js
@@ -24,9 +24,7 @@ export default RestSerializer.extend({
     },
 
     serialize(object, request) {
-        // Ember expects pluralized responses for the post, user, and invite models,
-        // and this shortcut will ensure that those models are pluralized
-        if (this.isModel(object) && ['post', 'user', 'invite'].includes(object.modelName)) {
+        if (this.isModel(object)) {
             object = new Collection(object.modelName, [object]);
         }