diff --git a/pkgs/by-name/pe/persepolis/0001-Allow-building-on-darwin.patch b/pkgs/by-name/pe/persepolis/0001-Allow-building-on-darwin.patch
deleted file mode 100644
index 46790103f3d1..000000000000
--- a/pkgs/by-name/pe/persepolis/0001-Allow-building-on-darwin.patch
+++ /dev/null
@@ -1,37 +0,0 @@
----
- setup.py | 13 +++++--------
- 1 file changed, 5 insertions(+), 8 deletions(-)
-
-diff --git a/setup.py b/setup.py
-index 985d28d..933f3df 100755
---- a/setup.py
-+++ b/setup.py
-@@ -24,13 +24,9 @@ import shutil
- # finding os platform
- os_type = platform.system()
- 
--if os_type == 'Linux' or os_type == 'FreeBSD' or os_type == 'OpenBSD':
--    from setuptools import setup, Command, find_packages
--    setuptools_available = True
--    print(os_type + " detected!")
--else:
--    print('This script is only work for GNU/Linux or BSD!')
--    sys.exit(1)
-+from setuptools import setup, Command, find_packages
-+setuptools_available = True
-+print(os_type + " detected!")
- 
- # Checking dependencies!
- not_installed = ''
-@@ -139,7 +136,7 @@ if sys.argv[1] == "test":
- 
- DESCRIPTION = 'Persepolis Download Manager'
- 
--if os_type == 'Linux':
-+if os_type in ['Linux', 'Darwin']:
-     DATA_FILES = [
-         ('/usr/share/man/man1/', ['man/persepolis.1.gz']),
-         ('/usr/share/applications/', ['xdg/com.github.persepolisdm.persepolis.desktop']),
--- 
-2.39.3 (Apple Git-145)
-
diff --git a/pkgs/by-name/pe/persepolis/0002-Fix-startup-crash-on-darwin.patch b/pkgs/by-name/pe/persepolis/0002-Fix-startup-crash-on-darwin.patch
deleted file mode 100644
index 50252c8cd72a..000000000000
--- a/pkgs/by-name/pe/persepolis/0002-Fix-startup-crash-on-darwin.patch
+++ /dev/null
@@ -1,41 +0,0 @@
----
- persepolis/scripts/mac_notification.py | 25 +++++++++----------------
- 1 file changed, 9 insertions(+), 16 deletions(-)
-
-diff --git a/persepolis/scripts/mac_notification.py b/persepolis/scripts/mac_notification.py
-index 4d69929..9a9a7cf 100644
---- a/persepolis/scripts/mac_notification.py
-+++ b/persepolis/scripts/mac_notification.py
-@@ -15,20 +15,13 @@
- 
- # native notification on mac! needs Xcode (latest version) installed and pyobjc
- # library from pip
--import Foundation
--import AppKit
--import objc
--
--NSUserNotification = objc.lookUpClass('NSUserNotification')
--NSUserNotificationCenter = objc.lookUpClass('NSUserNotificationCenter')
--
--
- def notifyMac(title, subtitle, info_text, delay=0):
--    notification = NSUserNotification.alloc().init()
--    notification.setTitle_(title)
--    notification.setSubtitle_(subtitle)
--    notification.setInformativeText_(info_text)
--    notification.setDeliveryDate_(Foundation.NSDate.dateWithTimeInterval_sinceDate_(
--        delay, Foundation.NSDate.date()))
--    NSUserNotificationCenter.defaultUserNotificationCenter(
--    ).scheduleNotification_(notification)
-+    print(f"""
-+Warning: Persepolis was installed from nixpkgs, which currently breaks notifications
-+         on macOS. Until https://github.com/NixOS/nixpkgs/issues/105156 is resolved,
-+         this cannot be fixed. The notification that should've been displayed was:
-+
-+         title: {title}
-+         subtitle: {subtitle}
-+         info_text: {info_text}
-+ """)
--- 
-2.39.3 (Apple Git-145)
-
diff --git a/pkgs/by-name/pe/persepolis/package.nix b/pkgs/by-name/pe/persepolis/package.nix
index 0aa47b37fe17..3105cd8621f3 100644
--- a/pkgs/by-name/pe/persepolis/package.nix
+++ b/pkgs/by-name/pe/persepolis/package.nix
@@ -8,39 +8,33 @@
 , libnotify
 , pulseaudio
 , sound-theme-freedesktop
+, pkg-config
+, meson
+, ninja
 }:
 
 python3.pkgs.buildPythonApplication rec {
   pname = "persepolis";
-  version = "4.0.0";
+  version = "4.0.1";
+  format = "other";
 
   src = fetchFromGitHub {
     owner = "persepolisdm";
     repo = "persepolis";
-    rev = "refs/tags/${version}";
-    hash = "sha256-2S6s/tWhI9RBFA26jkwxYTGeaok8S8zv/bY+Zr8TOak=";
+    rev = "57dc9d438bb3f126070a17c7a3677c45ea4dd332";
+    hash = "sha256-7OXAITFQJ2/aY0QmqlAo7if7cY7+T3j6PUjfJJV8Z2Q=";
   };
 
   patches = [
     # Upstream does currently not allow building from source on macOS. These patches can likely
     # be removed if https://github.com/persepolisdm/persepolis/issues/943 is fixed upstream
-    ./0001-Allow-building-on-darwin.patch
-    ./0002-Fix-startup-crash-on-darwin.patch
     ./0003-Search-PATH-for-aria2c-on-darwin.patch
     ./0004-Search-PATH-for-ffmpeg-on-darwin.patch
   ];
 
   postPatch = ''
-    sed -i "s|'persepolis = persepolis.__main__'|'persepolis = persepolis.scripts.persepolis:main'|" setup.py
-
-    # Automatically answer yes to all interactive questions during setup
-    substituteInPlace setup.py --replace-fail "answer = input(" "answer = 'y'#"
-
-    # Ensure dependencies with hard-coded FHS paths are properly detected
-    substituteInPlace setup.py --replace-fail "isdir(notifications_path)" "isdir('${sound-theme-freedesktop}/share/sounds/freedesktop')"
-
-    # Fix oversight in test script (can be removed once https://github.com/persepolisdm/persepolis/pull/942 is merged upstream)
-    substituteInPlace setup.py --replace-fail "sys.exit('0')" "sys.exit(0)"
+    # Ensure dependencies with hard-coded FHS dependencies are properly detected
+    substituteInPlace check_dependencies.py --replace-fail "isdir(notifications_path)" "isdir('${sound-theme-freedesktop}/share/sounds/freedesktop')"
   '';
 
   postInstall = ''
@@ -50,7 +44,7 @@ python3.pkgs.buildPythonApplication rec {
 
   # prevent double wrapping
   dontWrapQtApps = true;
-  nativeBuildInputs = [ qt5.wrapQtAppsHook ];
+  nativeBuildInputs = [ meson ninja pkg-config qt5.wrapQtAppsHook ];
 
   # feed args to wrapPythonApp
   makeWrapperArgs = [