diff --git a/pkgs/servers/memcached/default.nix b/pkgs/servers/memcached/default.nix
index 004822b906ca..681439bb9411 100644
--- a/pkgs/servers/memcached/default.nix
+++ b/pkgs/servers/memcached/default.nix
@@ -1,4 +1,4 @@
-{stdenv, fetchurl, cyrus_sasl, libevent}:
+{stdenv, fetchurl, fetchpatch, cyrus_sasl, libevent}:
 
 stdenv.mkDerivation rec {
   version = "1.5.21";
@@ -9,6 +9,16 @@ stdenv.mkDerivation rec {
     sha256 = "1x4jzrz09aq4nllkarn7d5x77gsys5l3nvfj8c7j4nvmvc30rlg3";
   };
 
+  patches = [
+    # Fixes compilation error on Darwin due to redeclaration of
+    # htonll. The fix should appear in 1.5.23.
+    # https://github.com/memcached/memcached/issues/598
+    (fetchpatch {
+      url = "https://github.com/memcached/memcached/commit/95c67710aaf5cfe188d94b510faef8c66d6f5604.diff";
+      sha256 = "0ab5l24p4n4fpx78ilmg7jvs9nl84pdza90jbpbx3ns5n23pqbfs";
+    })
+  ];
+
   configureFlags = [
      "ac_cv_c_endian=${if stdenv.hostPlatform.isBigEndian then "big" else "little"}"
   ];