diff --git a/pkgs/build-support/cc-wrapper/default.nix b/pkgs/build-support/cc-wrapper/default.nix
index b79697b33f0c..2539f52accf0 100644
--- a/pkgs/build-support/cc-wrapper/default.nix
+++ b/pkgs/build-support/cc-wrapper/default.nix
@@ -46,7 +46,7 @@ let
   # The wrapper scripts use 'cat' and 'grep', so we may need coreutils.
   coreutils_bin = if nativeTools then "" else getBin coreutils;
 
-  default_cxx_stdlib_compile=optionalString (targetPlatform.isLinux && !(cc.isGNU or false))
+  default_cxx_stdlib_compile = optionalString (targetPlatform.isLinux && !(cc.isGNU or false) && !nativeTools)
     "-isystem $(echo -n ${cc.gcc}/include/c++/*) -isystem $(echo -n ${cc.gcc}/include/c++/*)/$(${cc.gcc}/bin/gcc -dumpmachine)";
 
   dashlessTarget = stdenv.lib.replaceStrings ["-"] ["_"] targetPlatform.config;