diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index dd3df2310c9c..421fb59a8aaa 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10313,6 +10313,8 @@ in modules // {
 
     buildInputs = with self; [ cython ];
 
+    disabled = isPyPy;
+
     meta = {
       description = "Line-by-line profiler";
       homepage = https://github.com/rkern/line_profiler;