diff --git a/doc/languages-frameworks/python.section.md b/doc/languages-frameworks/python.section.md
index c1945adb1cd3..b44686b8cd54 100644
--- a/doc/languages-frameworks/python.section.md
+++ b/doc/languages-frameworks/python.section.md
@@ -1019,7 +1019,7 @@ buildPythonPackage rec {
 
 The `buildPythonPackage` mainly does four things:
 
-* In the `buildPhase`, it calls `${python.interpreter} setup.py bdist_wheel` to
+* In the `buildPhase`, it calls `${python.pythonForBuild.interpreter} setup.py bdist_wheel` to
   build a wheel binary zipfile.
 * In the `installPhase`, it installs the wheel file using `pip install *.whl`.
 * In the `postFixup` phase, the `wrapPythonPrograms` bash function is called to
@@ -1546,7 +1546,7 @@ of such package using the feature is `pkgs/tools/X11/xpra/default.nix`.
 As workaround install it as an extra `preInstall` step:
 
 ```shell
-${python.interpreter} setup.py install_data --install-dir=$out --root=$out
+${python.pythonForBuild.interpreter} setup.py install_data --install-dir=$out --root=$out
 sed -i '/ = data\_files/d' setup.py
 ```
 
diff --git a/pkgs/applications/misc/calibre/default.nix b/pkgs/applications/misc/calibre/default.nix
index d642a81d2f75..8a031a220068 100644
--- a/pkgs/applications/misc/calibre/default.nix
+++ b/pkgs/applications/misc/calibre/default.nix
@@ -149,7 +149,7 @@ stdenv.mkDerivation rec {
     export XDG_DATA_HOME=$out/share
     export XDG_UTILS_INSTALL_MODE="user"
 
-    ${python3Packages.python.interpreter} setup.py install --root=$out \
+    ${python3Packages.python.pythonForBuild.interpreter} setup.py install --root=$out \
       --prefix=$out \
       --libdir=$out/lib \
       --staging-root=$out \
diff --git a/pkgs/applications/networking/mailreaders/afew/default.nix b/pkgs/applications/networking/mailreaders/afew/default.nix
index bc27b91a97da..ac0687900f17 100644
--- a/pkgs/applications/networking/mailreaders/afew/default.nix
+++ b/pkgs/applications/networking/mailreaders/afew/default.nix
@@ -26,7 +26,7 @@ python3Packages.buildPythonApplication rec {
   outputs = [ "out" "doc" ];
 
   postBuild =  ''
-    ${python3Packages.python.interpreter} setup.py build_sphinx -b html,man
+    ${python3Packages.python.pythonForBuild.interpreter} setup.py build_sphinx -b html,man
   '';
 
   postInstall = ''
diff --git a/pkgs/applications/networking/p2p/zeronet-conservancy/default.nix b/pkgs/applications/networking/p2p/zeronet-conservancy/default.nix
index 75e7981af5b2..e1a2a3826447 100644
--- a/pkgs/applications/networking/p2p/zeronet-conservancy/default.nix
+++ b/pkgs/applications/networking/p2p/zeronet-conservancy/default.nix
@@ -23,7 +23,7 @@ python3Packages.buildPythonApplication rec {
   ];
 
   buildPhase = ''
-    ${python3Packages.python.interpreter} -O -m compileall .
+    ${python3Packages.python.pythonForBuild.interpreter} -O -m compileall .
   '';
 
   installPhase = ''
diff --git a/pkgs/applications/networking/p2p/zeronet/default.nix b/pkgs/applications/networking/p2p/zeronet/default.nix
index 02b0c91e2da9..07ea1707526d 100644
--- a/pkgs/applications/networking/p2p/zeronet/default.nix
+++ b/pkgs/applications/networking/p2p/zeronet/default.nix
@@ -18,7 +18,7 @@ python3Packages.buildPythonApplication rec {
   ];
 
   buildPhase = ''
-    ${python3Packages.python.interpreter} -O -m compileall .
+    ${python3Packages.python.pythonForBuild.interpreter} -O -m compileall .
   '';
 
   installPhase = ''
diff --git a/pkgs/applications/office/paperless-ngx/default.nix b/pkgs/applications/office/paperless-ngx/default.nix
index 61c607c422e8..b27c41581563 100644
--- a/pkgs/applications/office/paperless-ngx/default.nix
+++ b/pkgs/applications/office/paperless-ngx/default.nix
@@ -244,13 +244,13 @@ python.pkgs.buildPythonApplication rec {
   postBuild = ''
     # Compile manually because `pythonRecompileBytecodeHook` only works
     # for files in `python.sitePackages`
-    ${python.interpreter} -OO -m compileall src
+    ${python.pythonForBuild.interpreter} -OO -m compileall src
 
     # Collect static files
-    ${python.interpreter} src/manage.py collectstatic --clear --no-input
+    ${python.pythonForBuild.interpreter} src/manage.py collectstatic --clear --no-input
 
     # Compile string translations using gettext
-    ${python.interpreter} src/manage.py compilemessages
+    ${python.pythonForBuild.interpreter} src/manage.py compilemessages
   '';
 
   installPhase = ''
diff --git a/pkgs/applications/science/biology/quast/default.nix b/pkgs/applications/science/biology/quast/default.nix
index 0a33c9767319..e5ee4b53089f 100644
--- a/pkgs/applications/science/biology/quast/default.nix
+++ b/pkgs/applications/science/biology/quast/default.nix
@@ -27,7 +27,7 @@ pythonPackages.buildPythonApplication rec {
       --replace "/bin/bash" "${bash}/bin/bash"
     mkdir -p "$out/${python.sitePackages}"
     export PYTHONPATH="$out/${python.sitePackages}:$PYTHONPATH"
-    ${python.interpreter} setup.py install \
+    ${python.pythonForBuild.interpreter} setup.py install \
       --install-lib=$out/${python.sitePackages} \
       --prefix="$out"
   '';
diff --git a/pkgs/applications/science/logic/z3/default.nix b/pkgs/applications/science/logic/z3/default.nix
index 9ad48e79c933..f810a5a56739 100644
--- a/pkgs/applications/science/logic/z3/default.nix
+++ b/pkgs/applications/science/logic/z3/default.nix
@@ -47,7 +47,7 @@ let common = { version, sha256, patches ? [ ], tag ? "z3" }:
 
     configurePhase = concatStringsSep " "
       (
-        [ "${python.interpreter} scripts/mk_make.py --prefix=$out" ]
+        [ "${python.pythonForBuild.interpreter} scripts/mk_make.py --prefix=$out" ]
           ++ optional javaBindings "--java"
           ++ optional ocamlBindings "--ml"
           ++ optional pythonBindings "--python --pypkgdir=$out/${python.sitePackages}"
diff --git a/pkgs/development/interpreters/renpy/default.nix b/pkgs/development/interpreters/renpy/default.nix
index d9105ca29238..bee024829cef 100644
--- a/pkgs/development/interpreters/renpy/default.nix
+++ b/pkgs/development/interpreters/renpy/default.nix
@@ -59,14 +59,14 @@ stdenv.mkDerivation rec {
 
   buildPhase = with python3.pkgs; ''
     runHook preBuild
-    ${python.interpreter} module/setup.py build --parallel=$NIX_BUILD_CORES
+    ${python.pythonForBuild.interpreter} module/setup.py build --parallel=$NIX_BUILD_CORES
     runHook postBuild
   '';
 
   installPhase = with python3.pkgs; ''
     runHook preInstall
 
-    ${python.interpreter} module/setup.py install --prefix=$out
+    ${python.pythonForBuild.interpreter} module/setup.py install --prefix=$out
     mkdir -p $out/share/renpy
     cp -vr sdk-fonts gui launcher renpy the_question tutorial renpy.py $out/share/renpy
 
diff --git a/pkgs/development/libraries/science/chemistry/openmm/default.nix b/pkgs/development/libraries/science/chemistry/openmm/default.nix
index 85072f77da12..2ad84249758a 100644
--- a/pkgs/development/libraries/science/chemistry/openmm/default.nix
+++ b/pkgs/development/libraries/science/chemistry/openmm/default.nix
@@ -82,8 +82,8 @@ stdenv.mkDerivation rec {
       export OPENMM_LIB_PATH=$out/lib
       export OPENMM_INCLUDE_PATH=$out/include
       cd python
-      ${python3Packages.python.interpreter} setup.py build
-      ${python3Packages.python.interpreter} setup.py install --prefix=$out
+      ${python3Packages.python.pythonForBuild.interpreter} setup.py build
+      ${python3Packages.python.pythonForBuild.interpreter} setup.py install --prefix=$out
     '';
 
   postFixup = ''
diff --git a/pkgs/development/python-modules/bash_kernel/default.nix b/pkgs/development/python-modules/bash_kernel/default.nix
index ba4672a17746..cee1ee04e353 100644
--- a/pkgs/development/python-modules/bash_kernel/default.nix
+++ b/pkgs/development/python-modules/bash_kernel/default.nix
@@ -43,7 +43,7 @@ buildPythonPackage rec {
   '';
 
   postInstall = ''
-    ${python.interpreter} -m bash_kernel.install --prefix $out
+    ${python.pythonForBuild.interpreter} -m bash_kernel.install --prefix $out
   '';
 
   meta = {
diff --git a/pkgs/development/python-modules/bashlex/default.nix b/pkgs/development/python-modules/bashlex/default.nix
index cb02db36ada1..e1d635c18b69 100644
--- a/pkgs/development/python-modules/bashlex/default.nix
+++ b/pkgs/development/python-modules/bashlex/default.nix
@@ -20,7 +20,7 @@ buildPythonPackage rec {
 
   # workaround https://github.com/idank/bashlex/issues/51
   preBuild = ''
-    ${python.interpreter} -c 'import bashlex'
+    ${python.pythonForBuild.interpreter} -c 'import bashlex'
   '';
 
   nativeCheckInputs = [
diff --git a/pkgs/development/python-modules/manimpango/default.nix b/pkgs/development/python-modules/manimpango/default.nix
index 9b03caa6b103..443415470b05 100644
--- a/pkgs/development/python-modules/manimpango/default.nix
+++ b/pkgs/development/python-modules/manimpango/default.nix
@@ -49,7 +49,7 @@ buildPythonPackage rec {
   '';
 
   preBuild = ''
-    ${python.interpreter} setup.py build_ext --inplace
+    ${python.pythonForBuild.interpreter} setup.py build_ext --inplace
   '';
 
   pythonImportsCheck = [
diff --git a/pkgs/development/python-modules/pycuda/default.nix b/pkgs/development/python-modules/pycuda/default.nix
index e2a41cca4a3a..49fc12e17274 100644
--- a/pkgs/development/python-modules/pycuda/default.nix
+++ b/pkgs/development/python-modules/pycuda/default.nix
@@ -32,7 +32,7 @@ buildPythonPackage rec {
   };
 
   preConfigure = with lib.versions; ''
-    ${python.interpreter} configure.py --boost-inc-dir=${boost.dev}/include \
+    ${python.pythonForBuild.interpreter} configure.py --boost-inc-dir=${boost.dev}/include \
                           --boost-lib-dir=${boost}/lib \
                           --no-use-shipped-boost \
                           --boost-python-libname=boost_python${major python.version}${minor python.version} \
diff --git a/pkgs/development/python-modules/pygame/default.nix b/pkgs/development/python-modules/pygame/default.nix
index 751bb9c8ae94..d89ca3dde700 100644
--- a/pkgs/development/python-modules/pygame/default.nix
+++ b/pkgs/development/python-modules/pygame/default.nix
@@ -52,7 +52,7 @@ buildPythonPackage rec {
   ];
 
   preConfigure = ''
-    ${python.interpreter} buildconfig/config.py
+    ${python.pythonForBuild.interpreter} buildconfig/config.py
   '';
 
   checkPhase = ''
diff --git a/pkgs/development/python-modules/pygeos/default.nix b/pkgs/development/python-modules/pygeos/default.nix
index 67fa2e02aa59..f5e0bf87b1d2 100644
--- a/pkgs/development/python-modules/pygeos/default.nix
+++ b/pkgs/development/python-modules/pygeos/default.nix
@@ -30,8 +30,8 @@ buildPythonPackage rec {
   # for the package to function. Therefore override of buildPhase was
   # necessary.
   buildPhase = ''
-    ${python.interpreter} setup.py build_ext --inplace
-    ${python.interpreter} setup.py bdist_wheel
+    ${python.pythonForBuild.interpreter} setup.py build_ext --inplace
+    ${python.pythonForBuild.interpreter} setup.py bdist_wheel
   '';
 
   nativeCheckInputs = [
@@ -50,4 +50,3 @@ buildPythonPackage rec {
     maintainers = with maintainers; [ nialov ];
   };
 }
-
diff --git a/pkgs/development/python-modules/pymunk/default.nix b/pkgs/development/python-modules/pymunk/default.nix
index e75b4fa3a90f..ab6903b93187 100644
--- a/pkgs/development/python-modules/pymunk/default.nix
+++ b/pkgs/development/python-modules/pymunk/default.nix
@@ -31,7 +31,7 @@ buildPythonPackage rec {
   ];
 
   preBuild = ''
-    ${python.interpreter} setup.py build_ext --inplace
+    ${python.pythonForBuild.interpreter} setup.py build_ext --inplace
   '';
 
   nativeCheckInputs = [
diff --git a/pkgs/development/python-modules/pyqt/4.x.nix b/pkgs/development/python-modules/pyqt/4.x.nix
index 2652b5eb00b3..a0bf3f03f600 100644
--- a/pkgs/development/python-modules/pyqt/4.x.nix
+++ b/pkgs/development/python-modules/pyqt/4.x.nix
@@ -27,7 +27,7 @@ buildPythonPackage rec {
     ''}
 
     chmod +x configure.py
-    sed -i '1i#!${python.interpreter}' configure.py
+    sed -i '1i#!${python.pythonForBuild.interpreter}' configure.py
   '';
 
   configureScript = "./configure.py";
diff --git a/pkgs/development/python-modules/pyside2/default.nix b/pkgs/development/python-modules/pyside2/default.nix
index 2668699aa297..4fa3e757767d 100644
--- a/pkgs/development/python-modules/pyside2/default.nix
+++ b/pkgs/development/python-modules/pyside2/default.nix
@@ -70,7 +70,7 @@ stdenv.mkDerivation rec {
 
   postInstall = ''
     cd ../../..
-    ${python.interpreter} setup.py egg_info --build-type=pyside2
+    ${python.pythonForBuild.interpreter} setup.py egg_info --build-type=pyside2
     cp -r PySide2.egg-info $out/${python.sitePackages}/
   '';
 
diff --git a/pkgs/development/python-modules/pysvn/default.nix b/pkgs/development/python-modules/pysvn/default.nix
index db7848a9282a..33daf6af75df 100644
--- a/pkgs/development/python-modules/pysvn/default.nix
+++ b/pkgs/development/python-modules/pysvn/default.nix
@@ -37,8 +37,8 @@ buildPythonPackage rec {
 
   preConfigure = ''
     cd Source
-    ${python.interpreter} setup.py backport
-    ${python.interpreter} setup.py configure \
+    ${python.pythonForBuild.interpreter} setup.py backport
+    ${python.pythonForBuild.interpreter} setup.py configure \
       --apr-inc-dir=${apr.dev}/include \
       --apu-inc-dir=${aprutil.dev}/include \
       --pycxx-dir=${pycxx.dev}/include \
diff --git a/pkgs/development/python-modules/python-efl/default.nix b/pkgs/development/python-modules/python-efl/default.nix
index 847c167fa20b..046b32c2177a 100644
--- a/pkgs/development/python-modules/python-efl/default.nix
+++ b/pkgs/development/python-modules/python-efl/default.nix
@@ -31,11 +31,11 @@ buildPythonPackage rec {
   '';
 
   preBuild = ''
-    ${python.interpreter} setup.py build_ext
+    ${python.pythonForBuild.interpreter} setup.py build_ext
   '';
 
   installPhase = ''
-    ${python.interpreter} setup.py install --prefix=$out --single-version-externally-managed
+    ${python.pythonForBuild.interpreter} setup.py install --prefix=$out --single-version-externally-managed
   '';
 
   doCheck = false;
diff --git a/pkgs/development/python-modules/python-fontconfig/default.nix b/pkgs/development/python-modules/python-fontconfig/default.nix
index 4aabb208a90c..45c94cdb83b3 100644
--- a/pkgs/development/python-modules/python-fontconfig/default.nix
+++ b/pkgs/development/python-modules/python-fontconfig/default.nix
@@ -17,7 +17,7 @@ in buildPythonPackage rec {
   nativeBuildInputs = [ cython ];
 
   preBuild = ''
-    ${python.interpreter} setup.py build_ext -i
+    ${python.pythonForBuild.interpreter} setup.py build_ext -i
   '';
 
   checkPhase = ''
diff --git a/pkgs/development/python-modules/pywayland/default.nix b/pkgs/development/python-modules/pywayland/default.nix
index f5832449b0d7..2a681c4f4960 100644
--- a/pkgs/development/python-modules/pywayland/default.nix
+++ b/pkgs/development/python-modules/pywayland/default.nix
@@ -24,7 +24,7 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytestCheckHook ];
 
   postBuild = ''
-    ${python.interpreter} pywayland/ffi_build.py
+    ${python.pythonForBuild.interpreter} pywayland/ffi_build.py
   '';
 
   # Tests need this to create sockets
diff --git a/pkgs/development/python-modules/pywlroots/default.nix b/pkgs/development/python-modules/pywlroots/default.nix
index 2fdf0407c64f..fb03693574a1 100644
--- a/pkgs/development/python-modules/pywlroots/default.nix
+++ b/pkgs/development/python-modules/pywlroots/default.nix
@@ -36,7 +36,7 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytestCheckHook ];
 
   postBuild = ''
-    ${python.interpreter} wlroots/ffi_build.py
+    ${python.pythonForBuild.interpreter} wlroots/ffi_build.py
   '';
 
   pythonImportsCheck = [ "wlroots" ];
diff --git a/pkgs/development/python-modules/shiboken2/default.nix b/pkgs/development/python-modules/shiboken2/default.nix
index 53ea30ca6823..b736c17337a9 100644
--- a/pkgs/development/python-modules/shiboken2/default.nix
+++ b/pkgs/development/python-modules/shiboken2/default.nix
@@ -45,7 +45,7 @@ stdenv.mkDerivation {
 
   postInstall = ''
     cd ../../..
-    ${python.interpreter} setup.py egg_info --build-type=shiboken2
+    ${python.pythonForBuild.interpreter} setup.py egg_info --build-type=shiboken2
     cp -r shiboken2.egg-info $out/${python.sitePackages}/
     rm $out/bin/shiboken_tool.py
   '';
diff --git a/pkgs/development/python-modules/torch/default.nix b/pkgs/development/python-modules/torch/default.nix
index 86889be4ee16..fe1b005c8e3d 100644
--- a/pkgs/development/python-modules/torch/default.nix
+++ b/pkgs/development/python-modules/torch/default.nix
@@ -219,7 +219,7 @@ in buildPythonPackage rec {
 
   preBuild = ''
     export MAX_JOBS=$NIX_BUILD_CORES
-    ${python.interpreter} setup.py build --cmake-only
+    ${python.pythonForBuild.interpreter} setup.py build --cmake-only
     ${cmake}/bin/cmake build
   '';
 
diff --git a/pkgs/development/python-modules/wxPython/4.0.nix b/pkgs/development/python-modules/wxPython/4.0.nix
index 380fefbc4cd0..64123cafd4a1 100644
--- a/pkgs/development/python-modules/wxPython/4.0.nix
+++ b/pkgs/development/python-modules/wxPython/4.0.nix
@@ -69,11 +69,11 @@ buildPythonPackage rec {
   '';
 
   buildPhase = ''
-    ${python.interpreter} build.py -v --use_syswx dox etg --nodoc sip build_py
+    ${python.pythonForBuild.interpreter} build.py -v --use_syswx dox etg --nodoc sip build_py
   '';
 
   installPhase = ''
-    ${python.interpreter} setup.py install --skip-build --prefix=$out
+    ${python.pythonForBuild.interpreter} setup.py install --skip-build --prefix=$out
   '';
 
   passthru = { wxWidgets = wxGTK; };
diff --git a/pkgs/development/python-modules/wxPython/4.1.nix b/pkgs/development/python-modules/wxPython/4.1.nix
index 3198dbc004c3..4b3e62a2eece 100644
--- a/pkgs/development/python-modules/wxPython/4.1.nix
+++ b/pkgs/development/python-modules/wxPython/4.1.nix
@@ -129,11 +129,11 @@ buildPythonPackage rec {
   '';
 
   buildPhase = ''
-    ${python.interpreter} build.py -v build_wx dox etg --nodoc sip build_py
+    ${python.pythonForBuild.interpreter} build.py -v build_wx dox etg --nodoc sip build_py
   '';
 
   installPhase = ''
-    ${python.interpreter} setup.py install --skip-build --prefix=$out
+    ${python.pythonForBuild.interpreter} setup.py install --skip-build --prefix=$out
     wrapPythonPrograms
   '';
 
diff --git a/pkgs/development/python-modules/wxPython/4.2.nix b/pkgs/development/python-modules/wxPython/4.2.nix
index cd112f8511c3..3d4ddb1e7061 100644
--- a/pkgs/development/python-modules/wxPython/4.2.nix
+++ b/pkgs/development/python-modules/wxPython/4.2.nix
@@ -102,7 +102,7 @@ buildPythonPackage rec {
     export PATH="${wxGTK}/bin:$PATH"
     export SDL_CONFIG="${SDL.dev}/bin/sdl-config"
 
-    ${python.interpreter} build.py -v --use_syswx dox etg sip --nodoc build_py
+    ${python.pythonForBuild.interpreter} build.py -v --use_syswx dox etg sip --nodoc build_py
 
     runHook postBuild
   '';
@@ -111,7 +111,7 @@ buildPythonPackage rec {
   installPhase = ''
     runHook preInstall
 
-    ${python.interpreter} setup.py install --skip-build --prefix=$out
+    ${python.pythonForBuild.interpreter} setup.py install --skip-build --prefix=$out
     wrapPythonPrograms
 
     runHook postInstall
diff --git a/pkgs/development/python-modules/xattr/default.nix b/pkgs/development/python-modules/xattr/default.nix
index fa9620d9dab3..189042082f04 100644
--- a/pkgs/development/python-modules/xattr/default.nix
+++ b/pkgs/development/python-modules/xattr/default.nix
@@ -26,7 +26,7 @@ buildPythonPackage rec {
   doCheck = false;
 
   postBuild = ''
-    ${python.interpreter} -m compileall -f xattr
+    ${python.pythonForBuild.interpreter} -m compileall -f xattr
   '';
 
   pythonImportsCheck = [
diff --git a/pkgs/development/python-modules/xkbcommon/default.nix b/pkgs/development/python-modules/xkbcommon/default.nix
index f9320a4bca00..8bf77c24e3f4 100644
--- a/pkgs/development/python-modules/xkbcommon/default.nix
+++ b/pkgs/development/python-modules/xkbcommon/default.nix
@@ -24,7 +24,7 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytestCheckHook ];
 
   postBuild = ''
-    ${python.interpreter} xkbcommon/ffi_build.py
+    ${python.pythonForBuild.interpreter} xkbcommon/ffi_build.py
   '';
 
   pythonImportsCheck = [ "xkbcommon" ];
diff --git a/pkgs/development/tools/fdroidserver/default.nix b/pkgs/development/tools/fdroidserver/default.nix
index 07448b21bb80..fd15f24e5390 100644
--- a/pkgs/development/tools/fdroidserver/default.nix
+++ b/pkgs/development/tools/fdroidserver/default.nix
@@ -21,7 +21,7 @@ python.pkgs.buildPythonApplication rec {
   '';
 
   preConfigure = ''
-    ${python.interpreter} setup.py compile_catalog
+    ${python.pythonForBuild.interpreter} setup.py compile_catalog
   '';
 
   postInstall = ''
diff --git a/pkgs/development/tools/misc/ycmd/default.nix b/pkgs/development/tools/misc/ycmd/default.nix
index 3abcfabad779..2d01944dce41 100644
--- a/pkgs/development/tools/misc/ycmd/default.nix
+++ b/pkgs/development/tools/misc/ycmd/default.nix
@@ -29,7 +29,7 @@ stdenv.mkDerivation {
 
   buildPhase = ''
     export EXTRA_CMAKE_ARGS="-DPATH_TO_LLVM_ROOT=${llvmPackages.libllvm} -DUSE_SYSTEM_ABSEIL=true"
-    ${python.interpreter} build.py --system-libclang --clang-completer --ninja
+    ${python.pythonForBuild.interpreter} build.py --system-libclang --clang-completer --ninja
   '';
 
   dontConfigure = true;
diff --git a/pkgs/os-specific/linux/libnl/default.nix b/pkgs/os-specific/linux/libnl/default.nix
index 08a55134e773..c9eea70db992 100644
--- a/pkgs/os-specific/linux/libnl/default.nix
+++ b/pkgs/os-specific/linux/libnl/default.nix
@@ -21,7 +21,7 @@ stdenv.mkDerivation rec {
 
   postBuild = lib.optionalString (pythonSupport) ''
       cd python
-      ${python.interpreter} setup.py install --prefix=../pythonlib
+      ${python.pythonForBuild.interpreter} setup.py install --prefix=../pythonlib
       cd -
   '';
 
diff --git a/pkgs/servers/home-assistant/intents.nix b/pkgs/servers/home-assistant/intents.nix
index 7d46432f3a6b..8c8470113c4c 100644
--- a/pkgs/servers/home-assistant/intents.nix
+++ b/pkgs/servers/home-assistant/intents.nix
@@ -45,7 +45,7 @@ buildPythonPackage rec {
   postInstall = ''
     pushd ..
     # https://github.com/home-assistant/intents/blob/main/script/package#L18
-    ${python.interpreter} -m script.intentfest merged_output $out/${python.sitePackages}/home_assistant_intents/data
+    ${python.pythonForBuild.interpreter} -m script.intentfest merged_output $out/${python.sitePackages}/home_assistant_intents/data
     popd
   '';
 
diff --git a/pkgs/tools/audio/tts/default.nix b/pkgs/tools/audio/tts/default.nix
index cb1880af91c4..8096fc22a2c5 100644
--- a/pkgs/tools/audio/tts/default.nix
+++ b/pkgs/tools/audio/tts/default.nix
@@ -95,7 +95,7 @@ python.pkgs.buildPythonApplication rec {
     # cython modules are not installed for some reasons
     (
       cd TTS/tts/utils/monotonic_align
-      ${python.interpreter} setup.py install --prefix=$out
+      ${python.pythonForBuild.interpreter} setup.py install --prefix=$out
     )
   '';
 
diff --git a/pkgs/tools/backup/s3ql/default.nix b/pkgs/tools/backup/s3ql/default.nix
index 53836da12508..8738f5dc4e24 100644
--- a/pkgs/tools/backup/s3ql/default.nix
+++ b/pkgs/tools/backup/s3ql/default.nix
@@ -18,7 +18,7 @@ python3Packages.buildPythonApplication rec {
   ];
 
   preBuild = ''
-    ${python3Packages.python.interpreter} ./setup.py build_cython build_ext --inplace
+    ${python3Packages.python.pythonForBuild.interpreter} ./setup.py build_cython build_ext --inplace
   '';
 
   checkPhase = ''