diff --git a/pkgs/applications/science/biology/N3/default.nix b/pkgs/applications/science/biology/N3/default.nix
new file mode 100644
index 000000000000..feaea5b15342
--- /dev/null
+++ b/pkgs/applications/science/biology/N3/default.nix
@@ -0,0 +1,37 @@
+{ stdenv, fetchFromGitHub, cmake, makeWrapper,
+  perl, MNI-Perllib, GetoptTabular,
+  libminc, EBTKS }:
+
+stdenv.mkDerivation rec {
+  pname = "N3";
+  name  = "${pname}-1.0.20";
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "2fdd939f0f2b24a4039bc6a8ade4a190a1d8e75d";
+    sha256 = "13z21c4r09hna3q1csvcn4i7ws5ixbdaja6ch421xv6nydjh2w5g";
+  };
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ libminc EBTKS ];
+  propagatedBuildInputs = [ perl MNI-Perllib GetoptTabular ];
+
+  cmakeFlags = [ "-DLIBMINC_DIR=${libminc}/lib/" "-DEBTKS_DIR=${EBTKS}/lib/" ];
+
+  checkPhase = "ctest --output-on-failure";
+  # don't run the tests as they fail at least due to missing program wrappers in this phase ...
+
+  postFixup = ''
+    for p in $out/bin/*; do
+      wrapProgram $p --prefix PERL5LIB : $PERL5LIB
+    done
+  '';
+
+  meta = with stdenv.lib; {
+    homepage = "https://github.com/BIC-MNI/${pname}";
+    description = "MRI non-uniformity correction for MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 056b35f14263..51edd6d16e03 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -19749,6 +19749,10 @@ with pkgs;
 
   muscle = callPackage ../applications/science/biology/muscle/default.nix { };
 
+  n3 = callPackage ../applications/science/biology/N3 {
+    inherit (perlPackages) perl GetoptTabular MNI-Perllib;
+  };
+
   neuron = callPackage ../applications/science/biology/neuron {
     python = null;
   };