diff --git a/nixos/tests/php/pcre.nix b/nixos/tests/php/pcre.nix
index 57407477f4b8..8e37d5dcf97b 100644
--- a/nixos/tests/php/pcre.nix
+++ b/nixos/tests/php/pcre.nix
@@ -1,7 +1,7 @@
 let
   testString = "can-use-subgroups";
 in
-import ../make-test-python.nix ({ lib, php, ... }: {
+import ../make-test-python.nix ({ pkgs, lib, php, ... }: {
   name = "php-${php.version}-httpd-pcre-jit-test";
   meta.maintainers = lib.teams.php.members;
 
@@ -31,12 +31,22 @@ import ../make-test-python.nix ({ lib, php, ... }: {
         '';
     };
   };
-  testScript = { ... }:
-    ''
+  testScript = let
+    # PCRE JIT SEAlloc feature does not play well with fork()
+    # The feature needs to either be disabled or PHP configured correctly
+    # More information in https://bugs.php.net/bug.php?id=78927 and https://bugs.php.net/bug.php?id=78630
+    pcreJitSeallocForkIssue = pkgs.writeText "pcre-jit-sealloc-issue.php" ''
+      <?php
+      preg_match('/nixos/', 'nixos');
+      $pid = pcntl_fork();
+      pcntl_wait($pid);
+    '';
+  in ''
       machine.wait_for_unit("httpd.service")
       # Ensure php evaluation by matching on the var_dump syntax
       response = machine.succeed("curl -fvvv -s http://127.0.0.1:80/index.php")
       expected = 'string(${toString (builtins.stringLength testString)}) "${testString}"'
       assert expected in response, "Does not appear to be able to use subgroups."
+      machine.succeed("${php}/bin/php -f ${pcreJitSeallocForkIssue}")
     '';
 })
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 4bae0a7823cb..68a366770e83 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -15834,7 +15834,7 @@ with pkgs;
   php82 = callPackage ../development/interpreters/php/8.2.nix {
     stdenv = if stdenv.cc.isClang then llvmPackages.stdenv else stdenv;
     pcre2 = pcre2.override {
-      withJitSealloc = !stdenv.isDarwin;
+      withJitSealloc = false; # See https://bugs.php.net/bug.php?id=78927 and https://bugs.php.net/bug.php?id=78630
     };
   };
   php82Extensions = recurseIntoAttrs php82.extensions;
@@ -15844,7 +15844,7 @@ with pkgs;
   php81 = callPackage ../development/interpreters/php/8.1.nix {
     stdenv = if stdenv.cc.isClang then llvmPackages.stdenv else stdenv;
     pcre2 = pcre2.override {
-      withJitSealloc = !stdenv.isDarwin;
+      withJitSealloc = false; # See https://bugs.php.net/bug.php?id=78927 and https://bugs.php.net/bug.php?id=78630
     };
   };
   php81Extensions = recurseIntoAttrs php81.extensions;
@@ -15854,7 +15854,7 @@ with pkgs;
   php80 = callPackage ../development/interpreters/php/8.0.nix {
     stdenv = if stdenv.cc.isClang then llvmPackages.stdenv else stdenv;
     pcre2 = pcre2.override {
-      withJitSealloc = !stdenv.isDarwin;
+      withJitSealloc = false; # See https://bugs.php.net/bug.php?id=78927 and https://bugs.php.net/bug.php?id=78630
     };
   };
   php80Extensions = recurseIntoAttrs php80.extensions;