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+name = "version_check"
+version = "0.9.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "49874b5167b65d7193b8aba1567f5c7d93d001cafc34600cee003eda787e483f"
+
+[[package]]
+name = "want"
+version = "0.2.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b6395efa4784b027708f7451087e647ec73cc74f5d9bc2e418404248d679a230"
+dependencies = [
+ "futures",
+ "log",
+ "try-lock",
+]
+
+[[package]]
+name = "wasi"
+version = "0.10.0+wasi-snapshot-preview1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "1a143597ca7c7793eff794def352d41792a93c481eb1042423ff7ff72ba2c31f"
+
+[[package]]
+name = "wasi"
+version = "0.11.0+wasi-snapshot-preview1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "9c8d87e72b64a3b4db28d11ce29237c246188f4f51057d65a7eab63b7987e423"
+
+[[package]]
+name = "wasm-bindgen"
+version = "0.2.82"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "fc7652e3f6c4706c8d9cd54832c4a4ccb9b5336e2c3bd154d5cccfbf1c1f5f7d"
+dependencies = [
+ "cfg-if 1.0.0",
+ "wasm-bindgen-macro",
+]
+
+[[package]]
+name = "wasm-bindgen-backend"
+version = "0.2.82"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "662cd44805586bd52971b9586b1df85cdbbd9112e4ef4d8f41559c334dc6ac3f"
+dependencies = [
+ "bumpalo",
+ "log",
+ "once_cell",
+ "proc-macro2",
+ "quote",
+ "syn",
+ "wasm-bindgen-shared",
+]
+
+[[package]]
+name = "wasm-bindgen-macro"
+version = "0.2.82"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b260f13d3012071dfb1512849c033b1925038373aea48ced3012c09df952c602"
+dependencies = [
+ "quote",
+ "wasm-bindgen-macro-support",
+]
+
+[[package]]
+name = "wasm-bindgen-macro-support"
+version = "0.2.82"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5be8e654bdd9b79216c2929ab90721aa82faf65c48cdf08bdc4e7f51357b80da"
+dependencies = [
+ "proc-macro2",
+ "quote",
+ "syn",
+ "wasm-bindgen-backend",
+ "wasm-bindgen-shared",
+]
+
+[[package]]
+name = "wasm-bindgen-shared"
+version = "0.2.82"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "6598dd0bd3c7d51095ff6531a5b23e02acdc81804e30d8f07afb77b7215a140a"
+
+[[package]]
+name = "web-sys"
+version = "0.3.59"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ed055ab27f941423197eb86b2035720b1a3ce40504df082cac2ecc6ed73335a1"
+dependencies = [
+ "js-sys",
+ "wasm-bindgen",
+]
+
+[[package]]
+name = "webpki"
+version = "0.21.4"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b8e38c0608262c46d4a56202ebabdeb094cef7e560ca7a226c6bf055188aa4ea"
+dependencies = [
+ "ring",
+ "untrusted",
+]
+
+[[package]]
+name = "webpki-roots"
+version = "0.17.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "a262ae37dd9d60f60dd473d1158f9fbebf110ba7b6a5051c8160460f6043718b"
+dependencies = [
+ "webpki",
+]
+
+[[package]]
+name = "winapi"
+version = "0.2.8"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "167dc9d6949a9b857f3451275e911c3f44255842c1f7a76f33c55103a909087a"
+
+[[package]]
+name = "winapi"
+version = "0.3.9"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5c839a674fcd7a98952e593242ea400abe93992746761e38641405d28b00f419"
+dependencies = [
+ "winapi-i686-pc-windows-gnu",
+ "winapi-x86_64-pc-windows-gnu",
+]
+
+[[package]]
+name = "winapi-build"
+version = "0.1.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "2d315eee3b34aca4797b2da6b13ed88266e6d612562a0c46390af8299fc699bc"
+
+[[package]]
+name = "winapi-i686-pc-windows-gnu"
+version = "0.4.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ac3b87c63620426dd9b991e5ce0329eff545bccbbb34f3be09ff6fb6ab51b7b6"
+
+[[package]]
+name = "winapi-util"
+version = "0.1.5"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "70ec6ce85bb158151cae5e5c87f95a8e97d2c0c4b001223f33a334e3ce5de178"
+dependencies = [
+ "winapi 0.3.9",
+]
+
+[[package]]
+name = "winapi-x86_64-pc-windows-gnu"
+version = "0.4.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "712e227841d057c1ee1cd2fb22fa7e5a5461ae8e48fa2ca79ec42cfc1931183f"
+
+[[package]]
+name = "winreg"
+version = "0.6.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "b2986deb581c4fe11b621998a5e53361efe6b48a151178d0cd9eeffa4dc6acc9"
+dependencies = [
+ "winapi 0.3.9",
+]
+
+[[package]]
+name = "ws2_32-sys"
+version = "0.2.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "d59cefebd0c892fa2dd6de581e937301d8552cb44489cdff035c6187cb63fa5e"
+dependencies = [
+ "winapi 0.2.8",
+ "winapi-build",
+]
+
+[[package]]
+name = "xdg"
+version = "2.4.1"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0c4583db5cbd4c4c0303df2d15af80f0539db703fa1c68802d4cbbd2dd0f88f6"
+dependencies = [
+ "dirs",
+]
diff --git a/pkgs/development/python-modules/cmsis-pack-manager/default.nix b/pkgs/development/python-modules/cmsis-pack-manager/default.nix
new file mode 100644
index 000000000000..8c5c8c7afed1
--- /dev/null
+++ b/pkgs/development/python-modules/cmsis-pack-manager/default.nix
@@ -0,0 +1,77 @@
+{ lib
+, fetchPypi
+, rustPlatform
+, stdenv
+, Security
+, writeShellScriptBin
+, buildPythonPackage
+, setuptools-scm
+, appdirs
+, milksnake
+, pyyaml
+, hypothesis
+, jinja2
+, mock
+, pytestCheckHook
+}:
+let
+  pname = "cmsis-pack-manager";
+  version = "0.4.0";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "sha256-NeUG6PFI2eTwq5SNtAB6ZMA1M3z1JmMND29V9/O5sgw=";
+  };
+
+  native = rustPlatform.buildRustPackage {
+    name = "${pname}-${version}-native";
+
+    inherit src;
+
+    buildInputs = lib.optionals stdenv.isDarwin [
+      Security
+    ];
+
+    sourceRoot = "${pname}-${version}/rust";
+    cargoLock.lockFile = ./Cargo.lock;
+
+    postPatch = ''
+      cp ${./Cargo.lock} Cargo.lock
+    '';
+
+    cargoBuildFlags = [ "--lib" ];
+  };
+in
+buildPythonPackage rec {
+  inherit pname version src;
+
+  # The cargo build is already run in a separate derivation
+  postPatch = ''
+    substituteInPlace setup.py \
+        --replace "'cargo', 'build'," "'true',"
+  '';
+
+  nativeBuildInputs = [ setuptools-scm ];
+  propagatedBuildInputs = [ appdirs milksnake pyyaml ];
+
+  checkInputs = [ hypothesis jinja2 mock pytestCheckHook ];
+
+  preBuild = ''
+    mkdir -p rust/target/release/deps
+    ln -s ${native}/lib/libcmsis_cffi${stdenv.hostPlatform.extensions.sharedLibrary} rust/target/release/deps/
+  '';
+
+  preCheck = ''
+    # Otherwise the test uses a dummy library (missing all symbols)
+    ln -sf ../build/lib/cmsis_pack_manager/_native__lib${stdenv.hostPlatform.extensions.sharedLibrary} cmsis_pack_manager/_native__lib${stdenv.hostPlatform.extensions.sharedLibrary}
+  '';
+
+  pythonImportsCheck = [ "cmsis_pack_manager" ];
+
+  meta = with lib; {
+    description = "A Rust and Python module for handling CMSIS Pack files";
+    homepage = "https://github.com/pyocd/cmsis-pack-manager";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ frogamic sbruder ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index b89cd79705ff..7efc91541c7d 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1886,6 +1886,10 @@ in {
     inherit (pkgs) cmigemo;
   };
 
+  cmsis-pack-manager = callPackage ../development/python-modules/cmsis-pack-manager {
+    inherit (pkgs.darwin.apple_sdk.frameworks) Security;
+  };
+
   cmsis-svd = callPackage ../development/python-modules/cmsis-svd { };
 
   cntk = callPackage ../development/python-modules/cntk { };