diff --git a/pkgs/build-support/setup-hooks/reproducible-builds.sh b/pkgs/build-support/setup-hooks/reproducible-builds.sh
new file mode 100644
index 000000000000..2d8db6ff7d3c
--- /dev/null
+++ b/pkgs/build-support/setup-hooks/reproducible-builds.sh
@@ -0,0 +1,4 @@
+# Use the last part of the out path as hash input for the build.
+# This should ensure that it is deterministic across rebuilds of the same
+# derivation and not easily collide with other builds.
+export NIX_CFLAGS_COMPILE+=" -frandom-seed=${out##*/}"
diff --git a/pkgs/stdenv/generic/default.nix b/pkgs/stdenv/generic/default.nix
index eeddb584a3d5..c7c3bb9f3f3f 100644
--- a/pkgs/stdenv/generic/default.nix
+++ b/pkgs/stdenv/generic/default.nix
@@ -70,6 +70,7 @@ let
       ../../build-support/setup-hooks/move-sbin.sh
       ../../build-support/setup-hooks/move-lib64.sh
       ../../build-support/setup-hooks/set-source-date-epoch-to-latest.sh
+      ../../build-support/setup-hooks/reproducible-builds.sh
       # TODO use lib.optional instead
       (if hasCC then cc else null)
     ];