diff --git a/pkgs/development/python-modules/reedsolo/default.nix b/pkgs/development/python-modules/reedsolo/default.nix
index b219a7b23e97..44e2c3b9b449 100644
--- a/pkgs/development/python-modules/reedsolo/default.nix
+++ b/pkgs/development/python-modules/reedsolo/default.nix
@@ -1,4 +1,10 @@
-{ lib, buildPythonPackage, fetchFromGitHub, cython, nose }:
+{ lib
+, buildPythonPackage
+, fetchpatch
+, fetchFromGitHub
+, cython
+, nose
+}:
 
 buildPythonPackage rec {
   pname = "reedsolo";
@@ -12,6 +18,14 @@ buildPythonPackage rec {
     hash = "sha256-GUMdL5HclXxqMYasq9kUE7fCqOkjr1D20wjd/E+xPBk=";
   };
 
+  patches = [
+    (fetchpatch {
+      # python3.10 compat; https://github.com/tomerfiliba/reedsolomon/pull/38
+      url = "https://github.com/tomerfiliba/reedsolomon/commit/63e5bd9fc3ca503990c212eb2c77c10589e6d6c3.patch";
+      hash = "sha256-47g+jUsJEAyqGnlzRA1oSyc2XFPUOfH0EW+vcOJzsxI=";
+    })
+  ];
+
   nativeBuildInputs = [ cython ];
 
   checkInputs = [ nose ];