diff --git a/pkgs/applications/misc/gramps/default.nix b/pkgs/applications/misc/gramps/default.nix
index 7365d297e3b8..9424ceeee51f 100644
--- a/pkgs/applications/misc/gramps/default.nix
+++ b/pkgs/applications/misc/gramps/default.nix
@@ -29,7 +29,7 @@ in buildPythonApplication rec {
     sha256 = "00358nzyw686ypqv45imc5k9frcqnhla0hpx9ynna3iy6iz5006x";
   };
 
-  pythonPath = with pythonPackages; [ bsddb3 PyICU pygobject3 pycairo ];
+  pythonPath = with pythonPackages; [ bsddb3 pyicu pygobject3 pycairo ];
 
   # Same installPhase as in buildPythonApplication but without --old-and-unmanageble
   # install flag.
diff --git a/pkgs/development/python-modules/agate/default.nix b/pkgs/development/python-modules/agate/default.nix
index 29f580636480..e2b45293dab0 100644
--- a/pkgs/development/python-modules/agate/default.nix
+++ b/pkgs/development/python-modules/agate/default.nix
@@ -9,7 +9,7 @@
 , lxml
 , nose
 , parsedatetime
-, PyICU
+, pyicu
 , python-slugify
 , pytimeparse
 , pythonOlder
@@ -46,7 +46,7 @@ buildPythonPackage rec {
     glibcLocales
     lxml
     nose
-    PyICU
+    pyicu
     pytz
   ];
 
diff --git a/pkgs/development/python-modules/natsort/default.nix b/pkgs/development/python-modules/natsort/default.nix
index 065367e36dd6..c6e6a2795373 100644
--- a/pkgs/development/python-modules/natsort/default.nix
+++ b/pkgs/development/python-modules/natsort/default.nix
@@ -4,7 +4,7 @@
 , fetchPypi
 , glibcLocales
 , hypothesis
-, PyICU
+, pyicu
 , pytest-mock
 , pytestCheckHook
 , pythonOlder
@@ -24,7 +24,7 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [
     fastnumbers
-    PyICU
+    pyicu
   ];
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/normality/default.nix b/pkgs/development/python-modules/normality/default.nix
index a91489f1aded..2b3f5fd4021f 100644
--- a/pkgs/development/python-modules/normality/default.nix
+++ b/pkgs/development/python-modules/normality/default.nix
@@ -4,7 +4,7 @@
 , text-unidecode
 , chardet
 , banal
-, PyICU
+, pyicu
 , pytestCheckHook
 }:
 buildPythonPackage rec {
@@ -22,7 +22,7 @@ buildPythonPackage rec {
     text-unidecode
     chardet
     banal
-    PyICU
+    pyicu
   ];
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/pyicu/default.nix b/pkgs/development/python-modules/pyicu/default.nix
index 54c757c93915..5e34624b5401 100644
--- a/pkgs/development/python-modules/pyicu/default.nix
+++ b/pkgs/development/python-modules/pyicu/default.nix
@@ -7,12 +7,14 @@
 }:
 
 buildPythonPackage rec {
-  pname = "PyICU";
+  pname = "pyicu";
   version = "2.10.2";
+  format = "setuptools";
 
   src = fetchPypi {
-    inherit pname version;
-    sha256 = "sha256-DDMJ7qf6toV1B6zmJANRW2D+CWy/tPkNFPVf91xUQcE=";
+    pname = "PyICU";
+    inherit version;
+    hash = "sha256-DDMJ7qf6toV1B6zmJANRW2D+CWy/tPkNFPVf91xUQcE=";
   };
 
   nativeBuildInputs = [ icu ]; # for icu-config, but should be replaced with pkg-config
diff --git a/pkgs/development/python-modules/slob/default.nix b/pkgs/development/python-modules/slob/default.nix
index 72af69e3e7c2..363bd0ab62d7 100644
--- a/pkgs/development/python-modules/slob/default.nix
+++ b/pkgs/development/python-modules/slob/default.nix
@@ -2,7 +2,7 @@
 , buildPythonPackage
 , fetchFromGitHub
 , isPy3k
-, PyICU
+, pyicu
 , python
 }:
 
@@ -18,7 +18,7 @@ buildPythonPackage {
     sha256 = "01195hphjnlcvgykw143rf06s6y955sjc1r825a58vhjx7hj54zh";
   };
 
-  propagatedBuildInputs = [ PyICU ];
+  propagatedBuildInputs = [ pyicu ];
 
   checkPhase = ''
     ${python.interpreter} -m unittest slob
diff --git a/pkgs/servers/matrix-synapse/default.nix b/pkgs/servers/matrix-synapse/default.nix
index 6d4b18ae8772..c94700e19032 100644
--- a/pkgs/servers/matrix-synapse/default.nix
+++ b/pkgs/servers/matrix-synapse/default.nix
@@ -65,7 +65,7 @@ buildPythonApplication rec {
     psycopg2
     pyasn1
     pydantic
-    PyICU
+    pyicu
     pyjwt
     pymacaroons
     pynacl
diff --git a/pkgs/servers/nominatim/default.nix b/pkgs/servers/nominatim/default.nix
index 4b7f9e3e2577..3994177e0847 100644
--- a/pkgs/servers/nominatim/default.nix
+++ b/pkgs/servers/nominatim/default.nix
@@ -49,7 +49,7 @@ stdenv.mkDerivation rec {
     psycopg2
     psutil
     jinja2
-    PyICU
+    pyicu
     datrie
   ];
 
diff --git a/pkgs/tools/misc/xdxf2slob/default.nix b/pkgs/tools/misc/xdxf2slob/default.nix
index 4a89db07c45c..a24f9196efb9 100644
--- a/pkgs/tools/misc/xdxf2slob/default.nix
+++ b/pkgs/tools/misc/xdxf2slob/default.nix
@@ -11,7 +11,7 @@ python3Packages.buildPythonApplication {
     sha256 = "0m3dnc3816ja3kmik1wabb706dkqdf5sxvabwgf2rcrq891xcddd";
   };
 
-  propagatedBuildInputs = [ python3Packages.PyICU python3Packages.slob ];
+  propagatedBuildInputs = [ python3Packages.pyicu python3Packages.slob ];
 
   meta = with lib; {
     description = "Tool to convert XDXF dictionary files to slob format";
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 8223de074b81..75f5cf537a20 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -148,6 +148,7 @@ mapAliases ({
   pycryptodome-test-vectors = throw "pycryptodome-test-vectors has been removed because it is an internal package to pycryptodome"; # added 2022-05-28
   pyialarmxr = pyialarmxr-homeassistant; # added 2022-06-07
   pyialarmxr-homeassistant = throw "The package was removed together with the component support in home-assistant 2022.7.0"; # added 2022-07-07
+  PyICU = pyicu; # Added 2022-12-22
   pyjson5 = json5; # added 2022-08-28
   pylibgen = throw "pylibgen is unmaintained upstreamed, and removed from nixpkgs"; # added 2020-06-20
   PyLD = pyld; # added 2022-06-22
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 4ca17accf532..0f55887292b9 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8013,7 +8013,7 @@ self: super: with self; {
 
   pyicloud = callPackage ../development/python-modules/pyicloud { };
 
-  PyICU = callPackage ../development/python-modules/pyicu { };
+  pyicu = callPackage ../development/python-modules/pyicu { };
 
   pyimpfuzzy = callPackage ../development/python-modules/pyimpfuzzy {
     inherit (pkgs) ssdeep;