diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 4c12089795df..16f1e013df2b 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -6543,15 +6543,23 @@ let
   emacs = emacs23;
 
   emacs22 = callPackage ../applications/editors/emacs-22 {
-    /* Using cpp 4.5, we get:
+    stdenv =
+      if stdenv.isDarwin
 
-         make[1]: Entering directory `/tmp/nix-build-dhbj8qqmqxwp3iw6sjcgafsrwlwrix1f-emacs-22.3.drv-0/emacs-22.3/lib-src'
-         Makefile:148: *** recipe commences before first target.  Stop.
+      /* On Darwin, use Apple-GCC, otherwise:
+           configure: error: C preprocessor "cc -E -no-cpp-precomp" fails sanity check */
+      then overrideGCC stdenv gccApple
+
+      /* Using cpp 4.5, we get:
+
+           make[1]: Entering directory `/tmp/nix-build-dhbj8qqmqxwp3iw6sjcgafsrwlwrix1f-emacs-22.3.drv-0/emacs-22.3/lib-src'
+           Makefile:148: *** recipe commences before first target.  Stop.
+
+         Apparently, this is because `lib-src/Makefile' is generated by
+         processing `lib-src/Makefile.in' with cpp, and the escaping rules for
+         literal backslashes have changed.  */
+      else overrideGCC stdenv gcc44;
 
-       Apparently, this is because `lib-src/Makefile' is generated by
-       processing `lib-src/Makefile.in' with cpp, and the escaping rules for
-       literal backslashes have changed.  */
-    stdenv = overrideGCC stdenv gcc44;
     xaw3dSupport = getConfig [ "emacs" "xaw3dSupport" ] false;
     gtkGUI = getConfig [ "emacs" "gtkSupport" ] true;
   };