diff --git a/pkgs/applications/audio/milkytracker/default.nix b/pkgs/applications/audio/milkytracker/default.nix
index 8bc0aebba5a8..f22ccd08a8e8 100644
--- a/pkgs/applications/audio/milkytracker/default.nix
+++ b/pkgs/applications/audio/milkytracker/default.nix
@@ -29,7 +29,7 @@ stdenv.mkDerivation rec {
   '';
 
   preBuild=''
-    export CPATH=${zlib}/lib
+    export CPATH=${zlib.out}/lib
   '';
 
   buildInputs = [ SDL alsaLib autoconf automake libjack2 perl zlib zziplib ];
diff --git a/pkgs/applications/editors/texmacs/default.nix b/pkgs/applications/editors/texmacs/default.nix
index e415239d76fb..e51813459c6f 100644
--- a/pkgs/applications/editors/texmacs/default.nix
+++ b/pkgs/applications/editors/texmacs/default.nix
@@ -69,7 +69,7 @@ stdenv.mkDerivation rec {
   postFixup = ''
     bin="$out/libexec/TeXmacs/bin/texmacs.bin"
     rpath=$(patchelf --print-rpath "$bin")
-    patchelf --set-rpath "$rpath:${zlib}/lib" "$bin"
+    patchelf --set-rpath "$rpath:${zlib.out}/lib" "$bin"
   '';
 
   meta = {
diff --git a/pkgs/development/compilers/gcc/4.3/default.nix b/pkgs/development/compilers/gcc/4.3/default.nix
index e97ae93cd531..317bd5eb3ed5 100644
--- a/pkgs/development/compilers/gcc/4.3/default.nix
+++ b/pkgs/development/compilers/gcc/4.3/default.nix
@@ -142,7 +142,7 @@ stdenv.mkDerivation ({
 } // (if langJava then {
   postConfigure = ''
     make configure-gcc
-    sed -i gcc/Makefile -e 's@^CFLAGS = .*@& -I${zlib}/include@ ; s@^LDFLAGS = .*@& -L${zlib}/lib@'
+    sed -i gcc/Makefile -e 's@^CFLAGS = .*@& -I${zlib}/include@ ; s@^LDFLAGS = .*@& -L${zlib.out}/lib@'
     sed -i gcc/Makefile -e 's@^CFLAGS = .*@& -I${boehmgc}/include@ ; s@^LDFLAGS = .*@& -L${boehmgc.out}/lib -lgc@'
   '';
 } else {})
diff --git a/pkgs/development/libraries/tokyo-cabinet/default.nix b/pkgs/development/libraries/tokyo-cabinet/default.nix
index 7512e085449c..b8969588b3c5 100644
--- a/pkgs/development/libraries/tokyo-cabinet/default.nix
+++ b/pkgs/development/libraries/tokyo-cabinet/default.nix
@@ -12,7 +12,7 @@ stdenv.mkDerivation rec {
 
   postInstall =
     '' sed -i "$out/lib/pkgconfig/tokyocabinet.pc" \
-           -e 's|-lz|-L${zlib}/lib -lz|g;
+           -e 's|-lz|-L${zlib.out}/lib -lz|g;
                s|-lbz2|-L${bzip2.out}/lib -lbz2|g'
     '';
 
diff --git a/pkgs/development/mobile/androidenv/androidndk_r8e.nix b/pkgs/development/mobile/androidenv/androidndk_r8e.nix
index ee649eb89b47..a38d2d6b33cf 100644
--- a/pkgs/development/mobile/androidenv/androidndk_r8e.nix
+++ b/pkgs/development/mobile/androidenv/androidndk_r8e.nix
@@ -55,7 +55,7 @@ stdenv.mkDerivation rec {
         \( -type f -a -name "*.so*" \) -o \
         \( -type f -a -perm -0100 \) \
         \) -exec patchelf --set-interpreter ${stdenv.cc.libc.out}/lib/ld-*so.? \
-                          --set-rpath ${zlib}/lib:${ncurses.lib}/lib {} \;
+                          --set-rpath ${zlib.out}/lib:${ncurses.lib}/lib {} \;
     # fix ineffective PROGDIR / MYNDKDIR determination
     for i in ndk-build ndk-gdb ndk-gdb-py
     do
diff --git a/pkgs/development/ocaml-modules/camlzip/default.nix b/pkgs/development/ocaml-modules/camlzip/default.nix
index 2024f5a5ab8f..60590c6c1d5f 100644
--- a/pkgs/development/ocaml-modules/camlzip/default.nix
+++ b/pkgs/development/ocaml-modules/camlzip/default.nix
@@ -23,7 +23,7 @@ stdenv.mkDerivation {
   postPatch = ''
     substitute ${./META} META --subst-var-by VERSION "${version}"
     substituteInPlace Makefile \
-      --subst-var-by ZLIB_LIBDIR "${zlib}/lib" \
+      --subst-var-by ZLIB_LIBDIR "${zlib.out}/lib" \
       --subst-var-by ZLIB_INCLUDE "${zlib}/include"
   '';
 
diff --git a/pkgs/development/perl-modules/Compress-Raw-Zlib/default.nix b/pkgs/development/perl-modules/Compress-Raw-Zlib/default.nix
index 20362a51a7be..9314481cbcfe 100644
--- a/pkgs/development/perl-modules/Compress-Raw-Zlib/default.nix
+++ b/pkgs/development/perl-modules/Compress-Raw-Zlib/default.nix
@@ -12,7 +12,7 @@ buildPerlPackage rec {
     cat > config.in <<EOF
       BUILD_ZLIB   = False
       INCLUDE      = ${zlib}/include
-      LIB          = ${zlib}/lib
+      LIB          = ${zlib.out}/lib
       OLD_ZLIB     = False
       GZIP_OS_CODE = AUTO_DETECT
     EOF
diff --git a/pkgs/development/tools/build-managers/cargo/snapshot.nix b/pkgs/development/tools/build-managers/cargo/snapshot.nix
index 8f5467f63112..5a061e4b7c8d 100644
--- a/pkgs/development/tools/build-managers/cargo/snapshot.nix
+++ b/pkgs/development/tools/build-managers/cargo/snapshot.nix
@@ -39,7 +39,7 @@ stdenv.mkDerivation {
     ./install.sh "--prefix=$out"
   '' + (if stdenv.isLinux then ''
     patchelf --interpreter "${stdenv.glibc.out}/lib/${stdenv.cc.dynamicLinker}" \
-             --set-rpath "${stdenv.cc.cc}/lib/:${stdenv.cc.cc}/lib64/:${zlib}/lib" \
+             --set-rpath "${stdenv.cc.cc}/lib/:${stdenv.cc.cc}/lib64/:${zlib.out}/lib" \
              "$out/bin/cargo"
   '' else "") + postInstall;
 }
diff --git a/pkgs/games/openttd/default.nix b/pkgs/games/openttd/default.nix
index 65fab09d04dd..471387320563 100644
--- a/pkgs/games/openttd/default.nix
+++ b/pkgs/games/openttd/default.nix
@@ -34,7 +34,7 @@ stdenv.mkDerivation rec {
   prefixKey = "--prefix-dir=";
 
   configureFlags = [
-    "--with-zlib=${zlib}/lib/libz.a"
+    "--with-zlib=${zlib.out}/lib/libz.a"
     "--without-liblzo2"
   ];
 
diff --git a/pkgs/servers/meteor/default.nix b/pkgs/servers/meteor/default.nix
index 5e13b4520c9b..7412378f3dec 100644
--- a/pkgs/servers/meteor/default.nix
+++ b/pkgs/servers/meteor/default.nix
@@ -40,7 +40,7 @@ stdenv.mkDerivation rec {
     popd
     substituteInPlace $out/tools/cli/main.js \
       --replace "@INTERPRETER@" "$(cat $NIX_CC/nix-support/dynamic-linker)" \
-      --replace "@RPATH@" "${stdenv.cc.cc}/lib:${zlib}/lib" \
+      --replace "@RPATH@" "${stdenv.cc.cc}/lib:${zlib.out}/lib" \
       --replace "@PATCHELF@" "${patchelf}/bin/patchelf"
 
     # Patch node.
@@ -54,7 +54,7 @@ stdenv.mkDerivation rec {
     for p in $devBundle/mongodb/bin/mongo{,d}; do
       patchelf \
         --set-interpreter $(cat $NIX_CC/nix-support/dynamic-linker) \
-        --set-rpath "$(patchelf --print-rpath $p):${stdenv.cc.cc}/lib:${zlib}/lib" \
+        --set-rpath "$(patchelf --print-rpath $p):${stdenv.cc.cc}/lib:${zlib.out}/lib" \
         $p
     done
 
diff --git a/pkgs/stdenv/linux/make-bootstrap-tools-cross.nix b/pkgs/stdenv/linux/make-bootstrap-tools-cross.nix
index ed7314878a6f..6b562eef53c2 100644
--- a/pkgs/stdenv/linux/make-bootstrap-tools-cross.nix
+++ b/pkgs/stdenv/linux/make-bootstrap-tools-cross.nix
@@ -201,7 +201,7 @@ rec {
         cp -d ${gmpxx}/lib/libgmp*.so* $out/lib
         cp -d ${mpfr.out}/lib/libmpfr*.so* $out/lib
         cp -d ${libmpc}/lib/libmpc*.so* $out/lib
-        cp -d ${zlib}/lib/libz.so* $out/lib
+        cp -d ${zlib.out}/lib/libz.so* $out/lib
         cp -d ${libelf}/lib/libelf.so* $out/lib
         
         # TBD: Why are these needed for cross but not native tools?
diff --git a/pkgs/stdenv/linux/make-bootstrap-tools.nix b/pkgs/stdenv/linux/make-bootstrap-tools.nix
index 1011ae6689ad..d33d8f9fb663 100644
--- a/pkgs/stdenv/linux/make-bootstrap-tools.nix
+++ b/pkgs/stdenv/linux/make-bootstrap-tools.nix
@@ -114,7 +114,7 @@ rec {
         cp -d ${gmpxx}/lib/libgmp*.so* $out/lib
         cp -d ${mpfr.out}/lib/libmpfr*.so* $out/lib
         cp -d ${libmpc}/lib/libmpc*.so* $out/lib
-        cp -d ${zlib}/lib/libz.so* $out/lib
+        cp -d ${zlib.out}/lib/libz.so* $out/lib
         cp -d ${libelf}/lib/libelf.so* $out/lib
 
         # Copy binutils.
diff --git a/pkgs/tools/filesystems/yandex-disk/default.nix b/pkgs/tools/filesystems/yandex-disk/default.nix
index 42308947c07b..df3cca854ed0 100644
--- a/pkgs/tools/filesystems/yandex-disk/default.nix
+++ b/pkgs/tools/filesystems/yandex-disk/default.nix
@@ -43,7 +43,7 @@ stdenv.mkDerivation rec {
 
     ${patchelf}/bin/patchelf \
       --set-interpreter "$(cat $NIX_CC/nix-support/dynamic-linker)" \
-      --set-rpath "${zlib}/lib:${p.gcclib}" \
+      --set-rpath "${zlib.out}/lib:${p.gcclib}" \
       $out/bin/yandex-disk
   '';
 
diff --git a/pkgs/tools/graphics/pngcheck/default.nix b/pkgs/tools/graphics/pngcheck/default.nix
index 160badaf668b..d288e7018e60 100644
--- a/pkgs/tools/graphics/pngcheck/default.nix
+++ b/pkgs/tools/graphics/pngcheck/default.nix
@@ -13,7 +13,7 @@ stdenv.mkDerivation rec {
   # '';
 
   makefile = "Makefile.unx";
-  makeFlags = "ZPATH=${zlib}/lib";
+  makeFlags = "ZPATH=${zlib.out}/lib";
 
   buildInputs = [ zlib ];
 
diff --git a/pkgs/tools/networking/p2p/gtk-gnutella/default.nix b/pkgs/tools/networking/p2p/gtk-gnutella/default.nix
index 5f335c8f76a9..ec2821f4d818 100644
--- a/pkgs/tools/networking/p2p/gtk-gnutella/default.nix
+++ b/pkgs/tools/networking/p2p/gtk-gnutella/default.nix
@@ -16,7 +16,7 @@ stdenv.mkDerivation {
   nativeBuildInputs = [ bison pkgconfig ];
   buildInputs = [ glib gtk libxml2 gettext zlib ];
 
-  NIX_LDFLAGS = "-rpath ${zlib}/lib";
+  NIX_LDFLAGS = "-rpath ${zlib.out}/lib";
   configureScript = "./Configure";
   dontAddPrefix = true;
   configureFlags = "-d -e -D prefix=$out -D gtkversion=2 -D official=true";