diff --git a/crates/swc/tests/fixture/jest/issue-6540/input/.swcrc b/crates/swc/tests/fixture/jest/issue-6540/input/.swcrc
new file mode 100644
index 00000000000..bd05168a337
--- /dev/null
+++ b/crates/swc/tests/fixture/jest/issue-6540/input/.swcrc
@@ -0,0 +1,23 @@
+{
+    "jsc": {
+        "parser": {
+            "syntax": "typescript",
+            "tsx": false,
+            "dynamicImport": true,
+            "decorators": true
+        },
+        "transform": {
+            "legacyDecorator": true,
+            "hidden": {
+                "jest": true
+            }
+        },
+        "target": "es2016",
+        "loose": false,
+        "externalHelpers": false,
+        "keepClassNames": false
+    },
+    "module": {
+        "type": "commonjs"
+    }
+}
\ No newline at end of file
diff --git a/crates/swc/tests/fixture/jest/issue-6540/input/index.ts b/crates/swc/tests/fixture/jest/issue-6540/input/index.ts
new file mode 100644
index 00000000000..fcab8030929
--- /dev/null
+++ b/crates/swc/tests/fixture/jest/issue-6540/input/index.ts
@@ -0,0 +1,7 @@
+import foo from "./foo";
+
+jest.mock("./foo").mock("./bar");
+
+test("Foo is a mock", () => {
+    expect(jest.isMockFunction(foo)).toBe(true);
+});
diff --git a/crates/swc/tests/fixture/jest/issue-6540/output/index.ts b/crates/swc/tests/fixture/jest/issue-6540/output/index.ts
new file mode 100644
index 00000000000..38cbeb94c1a
--- /dev/null
+++ b/crates/swc/tests/fixture/jest/issue-6540/output/index.ts
@@ -0,0 +1,10 @@
+"use strict";
+jest.mock("./foo").mock("./bar");
+Object.defineProperty(exports, "__esModule", {
+    value: true
+});
+const _interopRequireDefault = require("@swc/helpers/lib/_interop_require_default.js").default;
+const _foo = /*#__PURE__*/ _interopRequireDefault(require("./foo"));
+test("Foo is a mock", ()=>{
+    expect(jest.isMockFunction(_foo.default)).toBe(true);
+});
diff --git a/crates/swc_ecma_ext_transforms/src/jest.rs b/crates/swc_ecma_ext_transforms/src/jest.rs
index 66af9e62bb8..7d3bed7f8b9 100644
--- a/crates/swc_ecma_ext_transforms/src/jest.rs
+++ b/crates/swc_ecma_ext_transforms/src/jest.rs
@@ -44,14 +44,13 @@ impl Jest {
                                     prop: MemberProp::Ident(prop),
                                     ..
                                 },
-                            ) => match &*callee.obj {
-                                Expr::Ident(i)
-                                    if i.sym == *"jest" && HOIST_METHODS.contains(&*prop.sym) =>
-                                {
+                            ) => {
+                                if is_jest(&callee.obj) && HOIST_METHODS.contains(&*prop.sym) {
                                     hoisted.push(T::from_stmt(stmt))
+                                } else {
+                                    new.push(T::from_stmt(stmt));
                                 }
-                                _ => new.push(T::from_stmt(stmt)),
-                            },
+                            }
                             _ => new.push(T::from_stmt(stmt)),
                         },
                         _ => new.push(T::from_stmt(stmt)),
@@ -80,3 +79,15 @@ impl VisitMut for Jest {
         self.visit_mut_stmt_like(stmts)
     }
 }
+
+fn is_jest(e: &Expr) -> bool {
+    match e {
+        Expr::Ident(i) => i.sym == *"jest",
+        Expr::Member(MemberExpr { obj, .. }) => is_jest(obj),
+        Expr::Call(CallExpr {
+            callee: Callee::Expr(callee),
+            ..
+        }) => is_jest(callee),
+        _ => false,
+    }
+}